MedTrace Logo

Colloid Osmotic Pressure During Heart Surgery in Children

NCT01397526 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 9

Last updated 2014-07-01

No results posted yet for this study

Summary

Clinical oedema is seen after open heart surgery with the use of cardiopulmonary bypass and hypothermia in children. The oedema formation is due to increased fluid transport from blood to tissue. This transcapillary fluid transport is dependent on differences in interstitial and plasma colloid osmotic pressure. The purpose of this investigation is to evaluate changes in interstitial colloid osmotic pressure before, under and after the use of cardiopulmonary bypass in children. The study hypothesis is that oedema developed during cardiopulmonary bypass and hypothermia is caused by increased micro vascular protein leakage and reduced colloid osmotic pressure gradient through the capillary membrane.

Conditions

  • Heart Defects, Congenital

Sponsors & Collaborators

  • Haukeland University Hospital

    collaborator OTHER

  • Oslo University Hospital

    lead OTHER

Principal Investigators

  • Gunnar Norgard, Prof. PhD · Oslo University Hospital

  • Ansgar Berg, Prof. PhD · Haukeland University Hospital

Eligibility

Min Age
1 Day
Max Age
13 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2011-07-31
Primary Completion
2013-05-31
Completion
2013-12-31

Countries

  • Norway

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01397526 on ClinicalTrials.gov