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Time-limited Specific Oral Tolerance Induction in Children With Severe Egg Allergy

NCT01379651 · Status: COMPLETED · Phase: PHASE1/PHASE2 · Type: INTERVENTIONAL · Enrollment: 20

Last updated 2011-09-20

Study results available
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Summary

To evaluate the efficacy of a 6-month specific oral tolerance induction (SOTI) protocol in inducing tolerance (maximal dose of raw egg emulsion tolerated) in children with severe IgE-mediated egg allergy and a history of at least 1 anaphylactic reaction after accidental exposure to egg.

Conditions

  • - Egg Hypersensitivity

Interventions

OTHER

Specific oral tolerance induction

Specific oral tolerance induction consisted in the administration of increasing amounts of raw emulsion egg

Sponsors & Collaborators

  • Ospedale Buon Consiglio Fatebenefratelli

    lead OTHER

Principal Investigators

  • Iride Dello Iacono, pediatrician · Unit of Pediatrics, Fatebenefratelli Hospital, Benevento, Italy

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
5 Years
Max Age
11 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2008-01-31
Primary Completion
2010-06-30
Completion
2010-06-30

Countries

  • Italy

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01379651 on ClinicalTrials.gov