MedTrace Logo

Electrophysiologic and Morphologic Assessment of the Substrate to Guide Implantation of Defibrillators in Dilated Cardiomyopathy

NCT01378572 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 200

Last updated 2011-06-22

No results posted yet for this study

Summary

With the present study the investigators intend to identify the morphologic and electrophysiologic substrate markers of increased arrhythmic risk in patients with dilated cardiomyopathy undergoing implantation of a defibrillator for the primary prevention of sudden cardiac death. Moreover, the investigators also aim to identify if there is any electrophysiological substrate modification at the time of the first arrhythmic event in these patients. To this aim, the investigators will prospectively correlate electroanatomic mapping and cardiac magnetic resonance findings with arrhythmic events, in order to identify substrate markers of increased arrhythmic risk in patients with dilated cardiomyopathy, who are therefore more likely to benefit from a defibrillator implantation. Furthermore, electroanatomic mapping will be repeated at the time of the first arrhythmic event and compared with that at baseline, in order to evaluate any electrophysiological substrate changes.

Conditions

  • Dilated Cardiomyopathy
  • Primary Prevention of Sudden Cardiac Death
  • Implantable Cardioverter Defibrillator

Sponsors & Collaborators

  • Texas Cardiac Arrhythmia Research Foundation

    collaborator OTHER

  • Cardiac Arrhythmia Research Center, Centro Cardiologico Monzino, Milan, Italy

    collaborator UNKNOWN

  • Policlinico Casilino ASL RMB, Rome, Italy

    collaborator UNKNOWN

  • Dell'Angelo Hospital, Mestre-Venice, Italy

    collaborator UNKNOWN

  • Catholic University of the Sacred Heart

    lead OTHER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2009-11-30

Countries

  • United States
  • Italy

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01378572 on ClinicalTrials.gov