Polymorphisms of the Thiazide's Receptor Gene SLC12A3 and Development of Hyponatremia
NCT01346891 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 40
Last updated 2011-07-06
Summary
The purpose of this study is to detect if there are any differences in the coding region of SLC12A3 gene in individuals who have had hyponatremia associated to the use of thiazides, and those thiazides consumers without hyponatremia that have demonstrated good tolerance to the drug.
Conditions
- Thiazide Diuretics Induced Hyponatremia
Sponsors & Collaborators
-
Sociedad Argentina de Hipertension Arterial (SAHA)
collaborator OTHER -
Hospital Italiano de Buenos Aires
lead OTHER
Principal Investigators
-
Diego H Giunta, MD · Hospital Italiano de Buenos Aires
Eligibility
- Min Age
- 21 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2010-07-31
Countries
- Argentina
More Related Trials
-
Study on Blood Pressure Variability and Frailty in the Older People
NCT06868069 ·Status: RECRUITING
-
Renin-angiotensin-aldosterone System Polymorphisms in Resistant Hypertension and Adverse Cardiovascular Events
NCT01173029 ·Status: COMPLETED
-
Institutional Registry of Hyponatremia
NCT01370473 ·Status: COMPLETED
-
Genetic Architecture of Natriuretic Peptides and Blood Pressure Response
NCT07118592 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Acute Effect of Agiotensin-(1-7) in Healthy and Hypertensive Subjects
NCT03001271 ·Status: UNKNOWN ·Phase: EARLY_PHASE1
-
Hypertension Prevention in Pre-Hypertensive Individuals
NCT00970931 ·Status: COMPLETED ·Phase: PHASE3
-
Early Metabolic Changes With Thiazide or Beta Blocker Therapy for Essential Hypertension
NCT00380289 ·Status: UNKNOWN ·Phase: NA
-
Target Organ Damage and Polymorphisms Vav-2 and Vav-3 in Hypertensive Subjects
NCT02022618 ·Status: COMPLETED
-
The Effect of Sodium Nitrite on Renal Function and Blood Pressure in Healthy Humans. A Dose-response Study
NCT02078908 ·Status: COMPLETED ·Phase: PHASE1
-
Prospective Study on Primary Aldosteronism in Resistant Hypertension
NCT04213963 ·Status: RECRUITING
-
Central Hemodynamic and Sodium Urinary
NCT03932422 ·Status: UNKNOWN
-
Natriuretic Peptide System as Therapy in Human Preclinical Left Ventricle Dysfunction
NCT00387621 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Study of Amiloride on Vascular Phenotypes in Young Adults With Prehypertension
NCT01308983 ·Status: UNKNOWN ·Phase: PHASE4
-
Chymase Angiotensin-(1-12) Axis In Hypertensive Disease
NCT05644769 ·Status: UNKNOWN ·Phase: PHASE4
-
Angiotensin-(1-7) Cardiovascular Effects in Aging
NCT05301192 ·Status: RECRUITING ·Phase: EARLY_PHASE1
-
A Prospective Study to Assess the Screening Value of N-terminal Pro-B-type Natriuretic Peptide (NT-proBNP) for the Identification of Patients That Benefit From Additional Cardiac Testing Prior to Vascular Surgery
NCT00519961 ·Status: UNKNOWN ·Phase: NA
-
Hyponatremia in the Prevention of Hospitalized Patients Falls
NCT03265691 ·Status: COMPLETED ·Phase: NA
-
Use of Impedance Cardiography and Applanation Tonometry for Prediction of the Antihypertensive Effect of Two Drugs
NCT03560804 ·Status: COMPLETED ·Phase: NA
-
Mechanism(s) Underlying Hypotensive Response to ARB/NEP Inhibition - Aim 1
NCT03738878 ·Status: TERMINATED ·Phase: PHASE4
-
Blood Pressure and Diurnal Variation in Sodium, Potassium, and Water Excretion
NCT00005204 ·Status: COMPLETED
-
Genetic Determinant of Blood Pressure Sensitivity to Salt Intake
NCT01706887 ·Status: TERMINATED ·Phase: NA
-
Validation of B-type Natriuretic Peptide With N-terminal Pro B-type Natriuretic Peptide in Perioperative Risk Assessment
NCT05352698 ·Status: COMPLETED
-
Benidipine-based Comparison of Angiotensin Receptors, β-blockers, or Thiazide Diuretics in Hypertensive Patients
NCT00135551 ·Status: COMPLETED ·Phase: PHASE4
-
Impact of Reducing Antihypertensive Treatment on Mortality in Frail Subjects With Low Systolic Blood Pressure (SBP).
NCT03453268 ·Status: COMPLETED ·Phase: NA
-
Diuretics and Angiotensin-Receptor Blocker Agents in Patients With Stage I Hypertension
NCT00971165 ·Status: COMPLETED ·Phase: PHASE3