The Role of Inflammation and Aging in HIV-Associated Cardiovascular Risk
NCT01333644 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 270
Last updated 2015-06-02
Summary
It is the central hypothesis of the investigators study that HIV disease is a pro-inflammatory condition, and that years of inflammation result in premature "aging' of the immune system ("immunosenescence"). Just as these changes are thought be causally associated with heart disease in the very old,the investigators postulate that these changes will be associated with early heart disease in the untreated and perhaps treated HIV disease. To address this hypothesis, the investigators will measure immunosenescence in a large cohort of patients who span the entire disease process.
Conditions
- HIV Infection
- Cardiovascular Disease
- Inflammation
Sponsors & Collaborators
- collaborator INDUSTRY
-
University of California, San Francisco
lead OTHER
Principal Investigators
-
Priscilla Hsue, MD · University of California, San Francisco
Eligibility
- Min Age
- 40 Years
- Max Age
- 80 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2010-04-30
- Primary Completion
- 2014-12-31
- Completion
- 2014-12-31
Countries
- United States
Study Locations
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