German Spondyloarthritis Inception Cohort

Summary

The German Spondyloarthritis Inception cohort (GESPIC) was started 2000 as a prospective, longitudinal, multicentre, nationwide study in Germany on patients with early SpA including ankylosing spondylitis (AS, also known as radiographic axial spondyloarthritis) and non-radiographic axial SpA. The objectives of GESPIC are to learn about the course of SpA during the very early stage of the disease, to appropriately assess the outcome including radiographic progression of patients after several years of follow-up, to identify outcome predictors, to assess quality of life, function, and costs (direct and indirect costs). GESPIC has been recently expanded to recruit patients with other forms of SpA / conditions associated with SpA: acute anterior uveitis, Crohn's disease as well as with psoriasis / axial psoriatic arthritis.

Conditions

• Ankylosing Spondylitis (AS) / Radiographic Axial SpA (r-axSpA)
• Non-radiographic Axial Spondyloarthritis (Nr-axSpA)
• Axial Psoriatic Arthritis (axPsA)
• Acute Anterior Uveitis (AAU)
• Crohn Disease (CD)
• Ulcerative Colitis (UC)

Sponsors & Collaborators

• German Federal Ministry of Education and Research

  collaborator OTHER_GOV

• AbbVie

  collaborator INDUSTRY

• Amgen

  collaborator INDUSTRY

• Centocor, Inc.

  collaborator INDUSTRY

• Schering-Plough

  collaborator INDUSTRY

• Wyeth is now a wholly owned subsidiary of Pfizer

  collaborator INDUSTRY

• Berlin Institute of Health

  collaborator OTHER

• Novartis

  collaborator INDUSTRY

• UCB Pharma

  collaborator INDUSTRY

• Charite University, Berlin, Germany

  lead OTHER

Principal Investigators

• Joachim Sieper, Prof. Dr. · Charite University, Berlin, Germany

• Martin Rudwaleit, Prof. Dr. · Charite University, Berlin, Germany

• Denis Poddubnyy, Prof. Dr. · Charite University, Berlin, Germany

• Fabian Proft, MD · Charite University, Berlin, Germany

Eligibility

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2000-07-31

Primary Completion

2030-07-31

Completion

2030-07-31

Countries

• Germany

Study Locations