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Genetic Susceptibility to Ankylosing Spondylitis (AS) by Functional Genomics Approach

NCT02525042 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 97

Last updated 2015-08-17

No results posted yet for this study

Summary

The main objective is to identify in the candidate regions of differentially expressed genes by comparing the transcriptome of dendritic cells derived from circulating monocytes between cases and controls. Cases and family controls will be matched on the presence of HLA-B27 and depending on haplotype association studies to correlate the differences of gene expression and genetic variations with susceptibility to AS.

Conditions

Sponsors & Collaborators

  • Assistance Publique - Hôpitaux de Paris

    lead OTHER

Principal Investigators

  • Maxime BREBAN, MD, PhD · Ambroise Paré Hospital, 92100 Boulogne-Billancourt, France

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2011-08-31
Primary Completion
2014-01-31

Countries

  • France

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02525042 on ClinicalTrials.gov