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Study of PTPN22 C1858T Polymorphism in Children and Adolescents of Greek Origin With T1DM

NCT01276743 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 200

Last updated 2014-02-28

No results posted yet for this study

Summary

The protein tyrosine phosphatase non-receptor type 22 (PTPN22) gene encodes a lymphoid-specific phosphatase (LYP) which is an important downregulatory factor of T cell activation. A PTPN22 polymorphism, C1858T, was found associated with T1DM in different Caucasian populations.

In this observational case-control study, we aimed at confirming the role of PTPN22, C1858T polymorphism in T1DM predisposition in a Greek population.

Conditions

  • Type 1 Diabetes Mellitus

Sponsors & Collaborators

  • Aristotle University Of Thessaloniki

    lead OTHER

Principal Investigators

  • Assimina Galli-Tsinopoulou, MD, PhD · Aristotle University Of Thessaloniki

Eligibility

Min Age
3 Years
Max Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2010-02-28
Primary Completion
2011-07-31
Completion
2013-02-28

Countries

  • Greece

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01276743 on ClinicalTrials.gov