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Determinants of Metabolic Control in Children With Type 1 Diabetes Mellitus

NCT06317454 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 800

Last updated 2024-03-19

No results posted yet for this study

Summary

A good metabolic control of type 1 diabetes mellitus (T1DM) is crucial to avoid long-term complications associated with the disease. Although recent evidences suggest that a good metabolic control of T1DM is partly independent of management intensity and could be anticipated since onset, factors that influence glycated haemoglobin (HbA1c) patterns remain poorly understood and are likely to be genetic.

While significant progress has been made in understanding of the genetic contribution to T1DM onset, very few studies have evaluated the role of genetic factors on T1DM metabolic control.

This study aims to create a comprehensive database of genetic and phenotypic data in a cohort of children and young adults with T1DM and to evaluate genetic and environmental factors that might predict trajectories in glycemic control

Conditions

  • Diabetes Mellitus, Type 1

Interventions

DIAGNOSTIC_TEST

Blood and saliva analysis

Phenotyping and genotyping characterization using blood and saliva

Sponsors & Collaborators

  • IRCCS Burlo Garofolo

    lead OTHER

Eligibility

Min Age
6 Years
Max Age
21 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-11-11
Primary Completion
2024-12-31
Completion
2024-12-31

Countries

  • Italy

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06317454 on ClinicalTrials.gov