Developing an Interdisciplinary Pharmacogenomic Treatment Approach to Reduce Medication Burden and Improve Outcomes
NCT01274065 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 38
Last updated 2015-01-14
Summary
There is no common rule as to how a drug will affect patients. This is due to the effect specific DNA sequences of genes have on drug response, by the effect they have on how medications are metabolized. The primary objective of this research is to optimize medication therapy and to reduce the number of medications used, specifically medications for people with developmental disabilities and co-occuring psychiatric illnesses.
Conditions
- Developmental Disabilities
Interventions
- GENETIC
-
Genetic analysis
The research team will review data following DNA sample analysis and identify variants in genes that result in impaired drug metabolism
Sponsors & Collaborators
-
Avera McKennan Hospital & University Health Center
lead OTHER
Principal Investigators
-
Timothy Soundy, MD · Avera McKennan Hospital & University Health Center
Eligibility
- Min Age
- 13 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2009-09-30
- Primary Completion
- 2014-11-30
- Completion
- 2014-11-30
More Related Trials
-
Study of Clinical and Molecular Manifestations of Genetic Disorders
NCT00001466 ·Status: COMPLETED
-
Next Generation to Identify Genetic Causes of Disease in Patients Participating in NICHD Clinical Protocols
NCT01375543 ·Status: COMPLETED
-
Effect of Functional Genetic Polymorphisms on Brain Morphology and Function
NCT01035723 ·Status: COMPLETED
-
Utility of PharmacoGenomics for Reducing Adverse Drug Effects
NCT02081872 ·Status: UNKNOWN
-
Preemptive Pharmacogenomics Testing Among Geriatric Patients
NCT05091879 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Identification and Characterization of Novel Non-Coding Variants That Contribute to Genetic Disorders
NCT04399694 ·Status: COMPLETED
-
Exome Sequencing in Autistic Spectrum Disorder
NCT01059201 ·Status: COMPLETED
-
Search for Phenotype-modifying Genes in Patients With Intellectual Disabilities.
NCT06706934 ·Status: NOT_YET_RECRUITING
-
Pediatric Reporting of Adult-Onset Genomic Results
NCT03832985 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
Pharmacogenomics to Improve Supportive Care Symptoms.
NCT06856122 ·Status: ENROLLING_BY_INVITATION
-
Trial of Preemptive Pharmacogenetics in Underserved Patients
NCT05141019 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Genetic and Metabolic Disease in Children
NCT02650622 ·Status: RECRUITING
-
Assessment of the Impact of Clinical Pharmacogenomics on Real and Potential Medication Use in Veterans
NCT04893395 ·Status: WITHDRAWN ·Phase: NA
-
Clinical Integration of Genetic Risk Assessment in Family Medicine
NCT00339794 ·Status: COMPLETED
-
Utility of Pharmacogenomic Testing in Patients With Gastrointestinal Disorders
NCT05572593 ·Status: COMPLETED ·Phase: NA
-
Inherited Reproductive Disorders
NCT01500447 ·Status: RECRUITING
-
Study of the Genetic Factors Involved in Autism and Related Disorders
NCT04727489 ·Status: RECRUITING
-
Pediatric Patients With Metabolic or Other Genetic Disorders
NCT02769949 ·Status: COMPLETED
-
Evaluating the Validity of a Genetic Risk Assessment Tool in Identifying Autism Spectrum Disorder
NCT01452061 ·Status: COMPLETED
-
Risk of Recurrence of de Novo Mutations: Research and Quantification of Paternal Germinal Mosaicism by the Combined Use of Genomic Tools
NCT04564235 ·Status: COMPLETED ·Phase: NA
-
Genetic Analysis of Uncommon Disease Presentations in Non-US Populations
NCT06595940 ·Status: RECRUITING
-
Transition From Research to Disclosure in Human Genetics
NCT00505466 ·Status: COMPLETED
-
Pharmacogenetics Associated With IV Ketamine
NCT04695405 ·Status: COMPLETED
-
A Study of the Impact of Genetic Testing on Clinical Decision Making and Patient Care
NCT02487888 ·Status: UNKNOWN ·Phase: NA
-
Action Medical Research
NCT02227381 ·Status: COMPLETED