CARDIA Brain MRI Substudy
NCT01273311 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 719
Last updated 2018-04-05
Summary
Background:
\- The Coronary Artery Risk Development in Young Adults (CARDIA) study is an investigation of cardiovascular risk factors among African-American and white young adults between 18 and 30 years of age, first recruited in 1985 86 from Birmingham, AL; Chicago, IL; Minneapolis, MN; and Oakland, CA. The study has examined a wide variety of risk factors, including insulin resistance, obesity, and diabetes. Based on 20 years of followup, the data provide evidence of an increase in the prevalence of many cardiovascular risk factors, as well as other factors that may lead to brain disease. To further evaluate these changes, the CARDIA Year 25 Exam will include a brain imaging component to study brain structure and function in a subset of CARDIA participants.
Objectives:
\- To conduct brain magnetic resonance imaging as part of a 25-year followup study on participants in the original CARDIA study of heart disease risk factors in young adults.
Eligibility:
\- Existing CARDIA study participants in the Minneapolis, MN, and Oakland, CA regions.
Design:
* Participants will be screened with a full medical history and physical examination. - Participants will have an MRI scan at the 25-year followup examination for the CARDIA study.
* No additional testing or treatment will be required for this protocol.
Conditions
Sponsors & Collaborators
-
National Institute on Aging (NIA)
lead NIH
Principal Investigators
-
Lenore J Launer, Ph.D. · National Institute on Aging (NIA)
Eligibility
- Min Age
- 35 Years
- Max Age
- 55 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2010-12-22
- Completion
- 2014-02-18
Countries
- United States
Study Locations
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