MedTrace Logo

Macrophage Migration Inhibitory Factor (MIF)- Cardiac Surgery

NCT01267721 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 100

Last updated 2014-10-08

No results posted yet for this study

Summary

It has been repeatedly demonstrated that cardiac surgery with the use of extracorporeal circulation elicits a systemic inflammatory response and provokes ischemia-reperfusion related oxidative stress which could further lead to the development of organ failure in critically ill patients. Perioperative levels of macrophage migration inhibitory factor (MIF) and other inflammatory mediators could be involved in adverse outcomes in cardiac surgery.

Conditions

  • Heart Surgery

Interventions

PROCEDURE

Blood sampling

Blood sampling at various time points. Additional 92 mL blood.

Sponsors & Collaborators

  • RWTH Aachen University

    lead OTHER

Principal Investigators

  • Steffen Rex, PD Dr. med. · RWTH Aachen University Hospital

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2011-01-31
Primary Completion
2012-12-31

Countries

  • Germany

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01267721 on ClinicalTrials.gov