SCH-900105 in Recurrent Glioblastoma
NCT01189513 · Status: WITHDRAWN · Phase: PHASE1 · Type: INTERVENTIONAL
Last updated 2012-02-20
Summary
The goal of this clinical research study is to find the highest tolerable dose of SCH 900105 that can be given to patients with glioblastoma before surgery. The safety of this drug will also be studied.
Conditions
Interventions
- DRUG
-
SCH 900105
10 mg/kg by vein every week on days 1, 8 and 15 of a 30 day cycle.
Sponsors & Collaborators
-
Schering-Plough
collaborator INDUSTRY -
M.D. Anderson Cancer Center
lead OTHER
Principal Investigators
-
John DeGroot, MD · UT MD Anderson Cancer Center
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2010-08-31
- Primary Completion
- 2011-01-31
- Completion
- 2011-01-31
More Related Trials
-
CNS Penetration, PK and PD of Preoperative CC-90010 in Progressive/Recurrent Diffuse Astrocytoma, Anaplastic Astrocytoma and Glioblastoma
NCT04047303 ·Status: TERMINATED ·Phase: PHASE1
-
Cediranib in Combination With Lomustine Chemotherapy in Recurrent Glioblastoma
NCT00777153 ·Status: COMPLETED ·Phase: PHASE3
-
GDC-0449 in Treating Patients With Recurrent Glioblastoma Multiforme That Can Be Removed by Surgery
NCT00980343 ·Status: COMPLETED ·Phase: PHASE2
-
Irinotecan Plus Carmustine in Treating Patients With Recurrent Primary Malignant Glioma
NCT00002988 ·Status: COMPLETED ·Phase: PHASE1
-
Adavosertib, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed or Recurrent Glioblastoma
NCT01849146 ·Status: COMPLETED ·Phase: PHASE1
-
Procarbazine in Treating Patients With Recurrent Brain Tumor
NCT00004004 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Genetically Modified Stem Cells and Irinotecan Hydrochloride in Treating Patients With Recurrent High-Grade Gliomas
NCT02055196 ·Status: WITHDRAWN ·Phase: PHASE1
-
Personalized Cancer Stem Cell High-Throughput Drug Screening for Glioblastoma
NCT05380349 ·Status: RECRUITING ·Phase: EARLY_PHASE1
-
Gamma-Secretase/Notch Signalling Pathway Inhibitor RO4929097 in Treating Patients With Recurrent or Progressive Glioblastoma
NCT01122901 ·Status: TERMINATED ·Phase: PHASE2
-
A Dose-Escalation Study in Participants With Recurrent Malignant Glioma
NCT01682187 ·Status: COMPLETED ·Phase: PHASE1
-
PF-00299804 in Adult Patients With Relapsed/Recurrent Glioblastoma
NCT01112527 ·Status: COMPLETED ·Phase: PHASE2
-
Combination Chemotherapy Following Radiation Therapy in Treating Patients With Malignant Glioma
NCT00005637 ·Status: COMPLETED ·Phase: PHASE1
-
Glufosfamide in Treating Patients With Recurrent Glioblastoma Multiforme
NCT00014300 ·Status: COMPLETED ·Phase: PHASE2
-
A Dose Finding Study of [177Lu]Lu-DOTA-TATE in Newly Diagnosed Glioblastoma in Combination With Standard of Care and in Recurrent Glioblastoma as a Single Agent.
NCT05109728 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
Volitinib in Treating Patients With Recurrent or Refractory Primary CNS Tumors
NCT03598244 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
Phase 1 Study of MPC-6827 and Carboplatin in Recurrent/Relapsed Glioblastoma Multiforme
NCT00635557 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
Gossypol (AT-101) and Temozolomide With or Without Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme
NCT00390403 ·Status: COMPLETED ·Phase: PHASE1
-
Dasatinib in Treating Patients With Recurrent Glioblastoma Multiforme or Gliosarcoma
NCT00423735 ·Status: COMPLETED ·Phase: PHASE2
-
A Phase 0 Study of AZD1775 in Recurrent GBM Patients
NCT02207010 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
Nivolumab, BMS-986205, and Radiation Therapy With or Without Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma
NCT04047706 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
Suramin in Treating Patients With Recurrent Primary Brain Tumors
NCT00002639 ·Status: COMPLETED ·Phase: PHASE2
-
Lonafarnib and Temozolomide in Treating Patients With Recurrent Primary Supratentorial Gliomas
NCT00083096 ·Status: UNKNOWN ·Phase: PHASE1
-
Lapatinib Ditosylate Before Surgery in Treating Patients With Recurrent High-Grade Glioma
NCT02101905 ·Status: COMPLETED ·Phase: PHASE1
-
Nitrocamptothecin in Treating Patients With Glioblastoma Multiforme
NCT00005826 ·Status: COMPLETED ·Phase: PHASE2
-
CC-8490 in Treating Patients With Recurrent or Refractory High-Grade Gliomas
NCT00074243 ·Status: COMPLETED ·Phase: PHASE1