Procarbazine in Treating Patients With Recurrent Brain Tumor
NCT00004004 · Status: COMPLETED · Phase: PHASE1/PHASE2 · Type: INTERVENTIONAL
Last updated 2013-06-21
Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.
PURPOSE: Phase I/II trial to study the effectiveness of procarbazine in treating patients who have progressive or recurrent astrocytoma, oligodendroglioma, or glioblastoma multiforme following treatment with radiation therapy.
Conditions
Interventions
- DRUG
-
procarbazine hydrochloride
Sponsors & Collaborators
-
National Cancer Institute (NCI)
collaborator NIH -
New Approaches to Brain Tumor Therapy Consortium
lead OTHER
Principal Investigators
-
Stuart A. Grossman, MD · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Study Design
- Purpose
- TREATMENT
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 1999-07-31
- Completion
- 2003-08-31
Countries
- United States
Study Locations
More Related Trials
-
Atrasentan in Treating Patients With Progressive or Recurrent Malignant Glioma
NCT00017264 ·Status: COMPLETED ·Phase: PHASE1
-
ATN-161 and Carboplatin in Treating Patients With Recurrent Malignant Glioma
NCT00352313 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Chemotherapy in Treating Patients With Progressive or Recurrent Brain Tumors
NCT00012038 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Carmustine Plus O6-benzylguanine in Treating Patients With Recurrent or Progressive Glioma
NCT00005081 ·Status: COMPLETED ·Phase: PHASE2
-
Karenitecin in Treating Patients With Recurrent Malignant Glioma
NCT00014521 ·Status: COMPLETED ·Phase: PHASE1
-
Carmustine in Treating Patients With Progressive or Recurrent Glioblastoma Multiforme
NCT00006656 ·Status: UNKNOWN ·Phase: PHASE2
-
ZD6474 to Treat Advanced Brain Cancer in Patients
NCT00272350 ·Status: COMPLETED ·Phase: PHASE1
-
Carmustine in Treating Adults With Recurrent Supratentorial Low-Grade Glioma
NCT00003467 ·Status: COMPLETED ·Phase: PHASE2
-
Carmustine in Treating Patients With Recurrent Malignant Glioma
NCT00004028 ·Status: COMPLETED ·Phase: PHASE1
-
Irinotecan in Treating Patients With Recurrent Glioma
NCT00003134 ·Status: COMPLETED ·Phase: PHASE2
-
SU-101 Compared With Procarbazine in Treating Patients With Glioblastoma Multiforme
NCT00003293 ·Status: COMPLETED ·Phase: PHASE3
-
Chemotherapy Followed by Radiation Therapy in Treating Adults With Supratentorial Glioma
NCT00002806 ·Status: COMPLETED ·Phase: PHASE2
-
SCH-900105 in Recurrent Glioblastoma
NCT01189513 ·Status: WITHDRAWN ·Phase: PHASE1
-
Acridine Carboxamide in Treating Patients With Recurrent Glioblastoma Multiforme
NCT00004937 ·Status: COMPLETED ·Phase: PHASE2
-
Chemotherapy in Treating Patients With Recurrent Malignant Glioma
NCT00002986 ·Status: COMPLETED ·Phase: PHASE1
-
Procarbazine and Isotretinoin in Treating Patients With Recurrent Primary Malignant Gliomas
NCT00003564 ·Status: WITHDRAWN ·Phase: PHASE3
-
Alanosine in Treating Patients With Progressive or Recurrent Malignant Gliomas
NCT00075894 ·Status: COMPLETED ·Phase: PHASE1
-
Carboxyamidotriazole + RT in Treating Patients Newly Diagnosed Supratentorial GBM
NCT00004146 ·Status: COMPLETED ·Phase: PHASE2
-
Carmustine Implants in Treating Patients With Brain Metastases
NCT00003878 ·Status: COMPLETED ·Phase: PHASE2
-
Topotecan in Treating Patients With Recurrent Brain Tumors
NCT00003372 ·Status: COMPLETED ·Phase: PHASE2
-
Dasatinib in Treating Patients With Recurrent Glioblastoma Multiforme or Gliosarcoma
NCT00423735 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of the Drugs Selumetinib vs. Carboplatin and Vincristine in Patients With Low-Grade Glioma
NCT04166409 ·Status: RECRUITING ·Phase: PHASE3
-
Carboplatin Plus Irinotecan in Treating Patients With Glioblastoma Multiforme
NCT00010036 ·Status: COMPLETED ·Phase: PHASE2
-
COL-3 in Treating Patients With Progressive or Recurrent Brain Tumors
NCT00004147 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Repeated Super-selective Intraarterial Cerebral Infusion Of Bevacizumab Plus Carboplatin For Treatment Of Relapsed/Refractory GBM And Anaplastic Astrocytoma
NCT01386710 ·Status: SUSPENDED ·Phase: PHASE1/PHASE2