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Peritoneal/ Serum Lactate Ratio in Relaparotomy

NCT01161849 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 60

Last updated 2011-01-04

No results posted yet for this study

Summary

Laparotomy performed for both emergency of elective surgery may by complicated by intrabdominal collection, anastomotic leakage, infarction and others. This conditions are able to induce peritoneal inflammation. Inflamed peritoneum are able to produce excess of lactate that the investigators can measure by collecting fluid from peritoneal drainage.

Drainage were left in abdomen for monitoring intrabdominal condition until the passage of stool or flatus. Minimum drainage of serum is present daily also in uncomplicated post operative period.

Serum lactate relates with increased systemic anaerobic metabolism such as SIRS, sepsis and systemic hypoperfusion and it is easy to measure with a blood gas analysis.

The investigators hypothesized that the increases of peritoneal/ serum lactate ratio could be an earlier, sensible, non-invasive, and economical marker of post surgical complications. The decision whether and when to perform a relaparotomy in secondary peritonitis is largely subjective and based on professional experience. Actually no existing scoring system aids in this decision.

The aim of this study is to demonstrate that this ratio could be and useful tool for the surgeon in this decisional process.

Conditions

  • Surgical Complications
  • Relaparotomy

Sponsors & Collaborators

  • Ospedale S. Giovanni Bosco

    lead OTHER

Principal Investigators

  • roberto bini, md · Chirurgia d'urgenza

  • Giovanni Ferrari, MD · Medicina d'urgenza

  • Renzo Leli, MD · Chirurgia d'urgenza

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2010-08-31
Primary Completion
2010-10-31
Completion
2010-12-31

Countries

  • Italy

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01161849 on ClinicalTrials.gov