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Continuous Passive Paracentesis for Intra-abdominal Hypertension

NCT04322201 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 60

Last updated 2020-03-26

No results posted yet for this study

Summary

Liver cirrhosis patients in Intensive Care present intra-abdominal hypertension and this is an independent risk factor for increased organ disfunction and mortality.

Patients will be randomized into intermittent or continuous passive paracentesis and the clinical results of these two strategies for preventing and treating intra-abdominal hypertension will compared.

Conditions

  • Ascites Hepatic
  • Cirrhosis, Liver
  • Hypertension, Intraabdominal
  • Critical Illness
  • Paracentesis

Interventions

DEVICE

continuous drainage of ascitic fluid using an intra-abdominal double lumen central venous catheter

Ultrasound-guided placement of an intra-abdominal double lumen central venous catheter, using aseptic Seldinger technique, for continuous drainage of ascitic fluid up to 7 days in Intensive Care

PROCEDURE

Ultrasound-guided intermittent large-volume paracentesis

Ultrasound-guided intermittent large-volume paracentesis through 14 Gauge catheter

Sponsors & Collaborators

  • NOVA Medical School

    collaborator OTHER

  • Centro Hospitalar de Lisboa Central

    lead OTHER

Principal Investigators

  • Rui A Pereira, MD, MSc · Centro Hospitalar de Lisboa Central

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-11-02
Primary Completion
2021-11-30
Completion
2022-05-31

Countries

  • Portugal

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04322201 on ClinicalTrials.gov