Vaccine Therapy in Treating Patients With Epstein-Barr Virus-Related Cancer
NCT01147991 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 16
Last updated 2012-02-28
Summary
RATIONALE: Vaccines made from a gene-modified virus may help the body build an effective immune response to kill tumor cells.
PURPOSE: This phase I trial is studying the side effects and best dose of vaccine therapy in treating patients with Epstein-Barr virus and cancer.
Conditions
- Gastric Cancer
- Head and Neck Cancer
- Lymphoma
- Lymphoproliferative Disorder
- Nonneoplastic Condition
Interventions
- BIOLOGICAL
-
EBNA1 C-terminal/LMP2 chimeric protein-expressing recombinant modified vaccinia Ankara vaccine
- OTHER
-
laboratory biomarker analysis
- OTHER
-
pharmacological study
Sponsors & Collaborators
- lead OTHER
Principal Investigators
-
Neil M Stevens, MD · University of Birmingham
Study Design
- Purpose
- TREATMENT
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2005-03-31
- Primary Completion
- 2011-04-30
- Completion
- 2011-04-30
Countries
- United Kingdom
Study Locations
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