The Gravity-VAP (Ventilator-Associated Pneumonia) Trial

Summary

This study is planned to compare, in patients sedated, intubated and mechanically ventilated, the efficacy and safety of the Lateral Trendelenburg position in comparison to the Semirecumbent Position to prevent incidence of ventilator-associated pneumonia (VAP).

Conditions

• Ventilator Associated Pneumonia

Interventions

OTHER

lateral-Trendelenburg position

lateral-Trendelenburg position of patients laying in the bed of the ICU, keeping trachea and tracheal tube horizontal, compared to the standard treatment (semirecumbent position) for the prevention of VAP

Sponsors & Collaborators

• Massachusetts General Hospital

  collaborator OTHER

• Azienda Ospedaliera San Gerardo di Monza

  collaborator OTHER

• Ospedale Nuovo del Mugello

  collaborator UNKNOWN

• Ospedale San Donato

  collaborator OTHER

• Azienda USL Reggio Emilia - IRCCS

  collaborator OTHER_GOV

• Ospedale S. Giovanni Bosco

  collaborator OTHER

• Fondazione IRCCS Policlinico San Matteo di Pavia

  collaborator OTHER

• Azienda Ospedaliero-Universitaria di Modena

  collaborator OTHER

• Ospedale Città di Sesto San Giovanni

  collaborator UNKNOWN

• Fondazione Policlinico Universitario Agostino Gemelli IRCCS

  collaborator OTHER

• Azienda Ospedaliero-Universitaria di Parma

  collaborator OTHER

• Goethe University

  collaborator OTHER

• Clinical Hospital Centre Zagreb

  collaborator OTHER

• Santa Chiara Hospital

  collaborator OTHER

• Hospital Clinic of Barcelona

  collaborator OTHER

• Policlinico Hospital

  lead OTHER

Study Design

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

SINGLE

Model

PARALLEL

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2010-11-30

Primary Completion

2015-04-30

Completion

2015-04-30

Countries

• Italy
• Spain

Study Locations