Everolimus in Treating Patients With Progressive or Recurrent, Unresectable, or Metastatic Thyroid Cancer
NCT01118065 · Status: UNKNOWN · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 42
Last updated 2013-08-12
Summary
RATIONALE: Everolimus may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth and by blocking blood flow to the tumor.
PURPOSE: This phase II trial is studying how well everolimus works in treating patients with progressive or recurrent, unresectable, or metastatic thyroid cancer.
Conditions
Interventions
- DRUG
Sponsors & Collaborators
-
Leiden University Medical Center
lead OTHER
Principal Investigators
-
Ellen Kapiteijn, MD, PhD · Leiden University Medical Center
Study Design
- Purpose
- TREATMENT
- Masking
- NONE
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2010-05-31
- Primary Completion
- 2012-05-31
Countries
- Netherlands
Study Locations
More Related Trials
-
Sorafenib Tosylate in Treating Patients With Locally Advanced, Metastatic, or Locally Recurrent Thyroid Cancer
NCT00095693 ·Status: TERMINATED ·Phase: PHASE2
-
Cabozantinib-S-Malate in Treating Patients With Refractory Thyroid Cancer
NCT01811212 ·Status: COMPLETED ·Phase: PHASE2
-
Sorafenib in Treating Patients With Advanced Anaplastic Thyroid Cancer
NCT00126568 ·Status: TERMINATED ·Phase: PHASE2
-
AE-941 in Treating Patients With Metastatic Kidney Cancer
NCT00005995 ·Status: COMPLETED ·Phase: PHASE3
-
Combretastatin A4 Phosphate in Treating Patients With Advanced Anaplastic Thyroid Cancer
NCT00060242 ·Status: COMPLETED ·Phase: PHASE2
-
Everolimus and Vatalanib in Treating Patients With Advanced Solid Tumors
NCT00655655 ·Status: COMPLETED ·Phase: PHASE1
-
Sorafenib Tosylate in Treating Patients With Metastatic, Locally Advanced, or Recurrent Medullary Thyroid Cancer
NCT00390325 ·Status: COMPLETED ·Phase: PHASE2
-
S0722: Everolimus in Treating Patients With Pleural Malignant Mesothelioma That Cannot Be Removed By Surgery
NCT00770120 ·Status: COMPLETED ·Phase: PHASE2
-
Lenvatinib and Pembrolizumab for the Treatment of Stage IVB Locally Advanced and Unresectable or Stage IVC Metastatic Anaplastic Thyroid Cancer
NCT04171622 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Erlotinib in Treating Patients With Metastatic and/or Recurrent Head and Neck Cancer
NCT00281866 ·Status: COMPLETED ·Phase: PHASE2
-
Phase II Trial of Sorafenib (Nexavar) in Patients With Advanced Thyroid Cancer
NCT00654238 ·Status: COMPLETED ·Phase: PHASE2
-
Efficacy and Safety Study of Sorafenib to Treat Advanced Medullary Thyroid Carcinoma
NCT01736878 ·Status: WITHDRAWN ·Phase: PHASE2
-
Tanespimycin in Treating Patients With Inoperable Locoregionally Advanced or Metastatic Thyroid Cancer
NCT00118248 ·Status: COMPLETED ·Phase: PHASE2
-
Encorafenib and Binimetinib With or Without Nivolumab in Treating Patients With Metastatic Radioiodine Refractory BRAF V600 Mutant Thyroid Cancer
NCT04061980 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Celecoxib in Treating Patients With Progressive Metastatic Differentiated Thyroid Cancer
NCT00061906 ·Status: COMPLETED ·Phase: PHASE2
-
Everolimus (RAD001) for the Treatment of Malignant Pleural Mesothelioma With Merlin/NF2 Loss as a Biomarker to Predict Sensitivity
NCT01024946 ·Status: COMPLETED ·Phase: PHASE2
-
Romidepsin in Treating Patients With Recurrent and/or Metastatic Thyroid Cancer That Has Not Responded to Radioactive Iodine
NCT00098813 ·Status: COMPLETED ·Phase: PHASE2
-
Sorafenib in Treating Patients With Metastatic or Unresectable Solid Tumors, Multiple Myeloma, or Non-Hodgkin's Lymphoma With or Without Impaired Liver or Kidney Function
NCT00118170 ·Status: COMPLETED ·Phase: PHASE1
-
Epirubicin and Thalidomide in Treating Patients With Liver Cancer
NCT00058487 ·Status: COMPLETED ·Phase: PHASE2
-
Temozolomide and Everolimus in Treating Patients With Stage IV Melanoma That Cannot be Removed by Surgery
NCT00521001 ·Status: COMPLETED ·Phase: PHASE2
-
A Phase 2, Open-label Study of AMG 706 to Treat Subjects With Locally Advanced or Metastatic Thyroid Cancer
NCT00121628 ·Status: COMPLETED ·Phase: PHASE2
-
Saracatinib in Treating Patients With Relapsed or Refractory Thymoma or Thymic Cancer
NCT00718809 ·Status: TERMINATED ·Phase: PHASE2
-
Vorinostat in Treating Patients With Metastatic or Unresectable Melanoma
NCT00121225 ·Status: COMPLETED ·Phase: PHASE2
-
Treatment of Patients With RAD001 With Progressive Sarcoma
NCT00767819 ·Status: COMPLETED ·Phase: PHASE2
-
Sorafenib Tosylate in Treating Younger Patients With Relapsed or Refractory Rhabdomyosarcoma, Wilms Tumor, Liver Cancer, or Thyroid Cancer
NCT01502410 ·Status: COMPLETED ·Phase: PHASE2