Sorafenib in Treating Patients With Advanced Anaplastic Thyroid Cancer
NCT00126568 · Status: TERMINATED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 20
Last updated 2018-01-19
Summary
This phase II trial is studying how well sorafenib works in treating patients with advanced anaplastic thyroid cancer. Sorafenib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth and by blocking blood flow to the tumor.
Conditions
- Anaplastic Thyroid Cancer
- Recurrent Thyroid Cancer
Interventions
- DRUG
-
sorafenib tosylate
Given orally
Sponsors & Collaborators
-
National Cancer Institute (NCI)
lead NIH
Principal Investigators
-
Panayiotis Savvides · Case Western Reserve University
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2005-06-30
- Primary Completion
- 2011-09-30
- Completion
- 2011-09-30
Countries
- United States
Study Locations
More Related Trials
-
Sorafenib Tosylate in Treating Patients With Progressive Metastatic Neuroendocrine Tumors
NCT00131911 ·Status: COMPLETED ·Phase: PHASE2
-
Combretastatin A4 Phosphate in Treating Patients With Advanced Anaplastic Thyroid Cancer
NCT00060242 ·Status: COMPLETED ·Phase: PHASE2
-
Tanespimycin in Treating Patients With Inoperable Locoregionally Advanced or Metastatic Thyroid Cancer
NCT00118248 ·Status: COMPLETED ·Phase: PHASE2
-
Efficacy and Safety Study of Sorafenib to Treat Advanced Medullary Thyroid Carcinoma
NCT01736878 ·Status: WITHDRAWN ·Phase: PHASE2
-
Sorafenib in Treating Patients With Stage III or Stage IV Melanoma That Cannot Be Removed By Surgery
NCT00119249 ·Status: COMPLETED ·Phase: PHASE2
-
Sorafenib in Treating Patients With Metastatic or Unresectable Solid Tumors, Multiple Myeloma, or Non-Hodgkin's Lymphoma With or Without Impaired Liver or Kidney Function
NCT00118170 ·Status: COMPLETED ·Phase: PHASE1
-
Sorafenib in Treating Patients With Relapsed or Refractory Multiple Myeloma
NCT00253578 ·Status: COMPLETED ·Phase: PHASE2
-
A Phase 2, Open-label Study of AMG 706 to Treat Subjects With Locally Advanced or Metastatic Thyroid Cancer
NCT00121628 ·Status: COMPLETED ·Phase: PHASE2
-
Irinotecan in Treating Patients With Metastatic or Inoperable Thyroid Cancer
NCT00100828 ·Status: TERMINATED ·Phase: PHASE2
-
Cabozantinib-S-Malate in Treating Patients With Refractory Thyroid Cancer
NCT01811212 ·Status: COMPLETED ·Phase: PHASE2
-
Sorafenib Tosylate With or Without Everolimus in Treating Patients With Advanced, Radioactive Iodine Refractory Hurthle Cell Thyroid Cancer
NCT02143726 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
S0505 Sorafenib in Treating Patients With Advanced Soft Tissue Sarcomas
NCT00217620 ·Status: COMPLETED ·Phase: PHASE2
-
Pazopanib Hydrochloride in Treating Patients With Advanced Thyroid Cancer
NCT00625846 ·Status: COMPLETED ·Phase: PHASE2
-
Study of Targeted Therapy vs. Chemotherapy in Patients With Thyroid Cancer
NCT06475989 ·Status: RECRUITING ·Phase: PHASE3
-
Sorafenib in Treating Patients With Advanced Malignant Solid Tumors
NCT00810394 ·Status: COMPLETED ·Phase: PHASE2
-
S0514 Sorafenib in Treating Patients With Unresectable or Metastatic Gallbladder Cancer or Cholangiocarcinoma
NCT00238212 ·Status: COMPLETED ·Phase: PHASE2
-
SU5416 in Treating Patients With Advanced or Recurrent Cancer of the Head and Neck
NCT00006361 ·Status: COMPLETED ·Phase: PHASE2
-
RAD001 for Patients With Radioiodine Refractory Thyroid Cancer
NCT00936858 ·Status: COMPLETED ·Phase: PHASE2
-
Sorafenib in Treating Patients With Soft Tissue Sarcomas (Extremity Sarcoma Closed to Entry as of 5/30/07)
NCT00330421 ·Status: COMPLETED ·Phase: PHASE2
-
Sorafenib Tosylate in Treating Younger Patients With Relapsed or Refractory Rhabdomyosarcoma, Wilms Tumor, Liver Cancer, or Thyroid Cancer
NCT01502410 ·Status: COMPLETED ·Phase: PHASE2
-
Sorafenib and TRC105 in Hepatocellular Cancer
NCT01306058 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Trametinib in Increasing Tumoral Iodine Incorporation in Patients With Recurrent or Metastatic Thyroid Cancer
NCT02152995 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Sorafenib Tosylate and Hypoxia-Activated Prodrug TH-302 in Treating Patients With Advanced Kidney Cancer or Liver Cancer That Cannot Be Removed By Surgery
NCT01497444 ·Status: COMPLETED ·Phase: PHASE1
-
Everolimus in Treating Patients With Progressive or Recurrent, Unresectable, or Metastatic Thyroid Cancer
NCT01118065 ·Status: UNKNOWN ·Phase: PHASE2
-
Celecoxib in Treating Patients With Progressive Metastatic Differentiated Thyroid Cancer
NCT00061906 ·Status: COMPLETED ·Phase: PHASE2