Epirubicin and Thalidomide in Treating Patients With Liver Cancer
NCT00058487 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 12
Last updated 2013-07-18
Summary
RATIONALE: Drugs used in chemotherapy such as epirubicin use different ways to stop tumor cells from dividing so they stop growing or die. Thalidomide may stop the growth of hepatocellular (liver) cancer by stopping blood flow to the tumor. Combining epirubicin with thalidomide may kill more tumor cells.
PURPOSE: Phase II trial to study the effectiveness of combining epirubicin with thalidomide in treating patients who have unresectable or metastatic liver cancer.
Conditions
Interventions
- DRUG
-
epirubicin hydrochloride
- DRUG
-
thalidomide
Sponsors & Collaborators
-
National Cancer Institute (NCI)
collaborator NIH - lead OTHER
Principal Investigators
-
Andrew X. Zhu, MD, PhD · Dana-Farber Cancer Institute
Study Design
- Purpose
- TREATMENT
- Masking
- NONE
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2001-12-31
- Completion
- 2007-01-31
Countries
- United States
Study Locations
More Related Trials
-
Thalidomide in Treating Patients With Recurrent or Persistent Endometrial Cancer
NCT00025467 ·Status: COMPLETED ·Phase: PHASE2
-
Thalidomide in Treating Patients With Refractory or Resistant Epithelial Ovarian Cancer
NCT00016224 ·Status: COMPLETED ·Phase: PHASE2
-
Chronic Thalidomide Administration in Patients Undergoing Chemoembolization for Unresectable Hepatocellular Cancer
NCT00006198 ·Status: UNKNOWN ·Phase: PHASE2
-
A Trial of Thalidomide and Capecitabine in Metastatic Renal Cell Carcinoma
NCT00226980 ·Status: COMPLETED ·Phase: PHASE2
-
Thalidomide in Treating Patients With Metastatic Neuroendocrine Tumors
NCT00027638 ·Status: COMPLETED ·Phase: PHASE2
-
Thalidomide in Treating Patients With Recurrent or Persistent Cancer of the Uterus
NCT00025220 ·Status: COMPLETED ·Phase: PHASE2
-
Thalidomide Combined With Chemotherapy and Monotherapy for Maintenance Treatment for Her2-negative Advanced GC
NCT05198856 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
Combination Chemotherapy Plus Thalidomide in Treating Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer
NCT00025285 ·Status: COMPLETED ·Phase: PHASE2
-
Thalidomide in Treating Patients With Recurrent or Persistent Carcinosarcoma of the Uterus
NCT00025506 ·Status: COMPLETED ·Phase: PHASE2
-
S0508: Thalidomide and Temozolomide in Treating Patients With Stage IV Melanoma That Cannot Be Removed By Surgery
NCT00104988 ·Status: COMPLETED ·Phase: PHASE2
-
Temozolomide, Thalidomide, and Lomustine in Treating Patients With Unresectable Stage III or Stage IV Melanoma
NCT00072345 ·Status: COMPLETED ·Phase: PHASE2
-
Irinotecan in Treating Patients With Metastatic or Inoperable Thyroid Cancer
NCT00100828 ·Status: TERMINATED ·Phase: PHASE2
-
A Trial of Thalidomide, Celecoxib, Etoposide and Cyclophosphamide in Patients With Relapsed or Progressive Cancer
NCT00165451 ·Status: COMPLETED ·Phase: PHASE2
-
Thalidomide in Treating Patients Who Have Undergone Surgery and Chemotherapy for Cancer That Has Spread Throughout the Abdomen Due to Colorectal Cancer or Appendix Cancer
NCT00310076 ·Status: COMPLETED ·Phase: PHASE2
-
Thalidomide and SU5416 in Treating Patients With Metastatic Melanoma
NCT00017316 ·Status: COMPLETED ·Phase: PHASE2
-
Interferon Alfa-2b With or Without Thalidomide in Treating Patients With Metastatic or Unresectable Kidney Cancer
NCT00005966 ·Status: COMPLETED ·Phase: PHASE3
-
Thalidomide and Docetaxel in Treating Patients With Advanced Cancer
NCT00049296 ·Status: COMPLETED ·Phase: PHASE1
-
Thalidomide in Treating Patients With Gynecologic Sarcomas
NCT00006005 ·Status: COMPLETED ·Phase: PHASE2
-
Sorafenib Tosylate in Treating Patients With Locally Advanced, Metastatic, or Locally Recurrent Thyroid Cancer
NCT00095693 ·Status: TERMINATED ·Phase: PHASE2
-
Surgery With or Without Thalidomide in Treating Patients With Recurrent or Metastatic Colorectal Cancer
NCT00019747 ·Status: TERMINATED ·Phase: PHASE2
-
Carboplatin, Gemcitabine, and Thalidomide in Patients Undergoing Surgery for Stage II or III Non-Small Cell Lung Cancer
NCT00281827 ·Status: TERMINATED ·Phase: PHASE2
-
Combination Therapy With 5-Fluorouracil, Interferon-an Interleukin-2, & Thalidomide for Metastatic, Advanced or Recurrent Renal Cell Carcinoma
NCT00277017 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Temozolomide and Everolimus in Treating Patients With Stage IV Melanoma That Cannot be Removed by Surgery
NCT00521001 ·Status: COMPLETED ·Phase: PHASE2
-
2-Methoxyestradiol in Treating Patients With Advanced Solid Tumors
NCT00028821 ·Status: COMPLETED ·Phase: PHASE1
-
Thalidomide in Treating Patients With Extensive-Stage Small Cell Lung Cancer
NCT00053300 ·Status: COMPLETED ·Phase: PHASE2