Potential Biomarkers for Bevacizumab-Induced High Blood Pressure in Patients With Solid Tumor
NCT01096381 · Status: TERMINATED · Type: OBSERVATIONAL · Enrollment: 8
Last updated 2012-02-27
Summary
RATIONALE: Studying samples of blood and urine in the laboratory from patients with cancer receiving bevacizumab may help doctors learn more about changes that occur in DNA and identify biomarkers related to high blood pressure.
PURPOSE: This phase I trial is studying potential biomarkers for bevacizumab-induced high blood pressure in patients with malignant solid tumors, including breast cancer, colorectal cancer, non-small cell lung cancer, head and neck cancer, ovarian cancer, fallopian tube cancer, or primary peritoneal carcinoma.
Conditions
- Breast Cancer
- Cardiovascular Complications
- Colorectal Cancer
- Fallopian Tube Cancer
- Head and Neck Cancer
- Lung Cancer
- Ovarian Cancer
- Peritoneal Cavity Cancer
- Unspecified Adult Solid Tumor, Protocol Specific
Interventions
- OTHER
-
laboratory biomarker analysis
Blood collection
- OTHER
-
questionnaire administration
Survey regarding baseline health and activity level.
Sponsors & Collaborators
-
National Cancer Institute (NCI)
collaborator NIH -
Vanderbilt-Ingram Cancer Center
lead OTHER
Principal Investigators
-
Ingrid Mayer, M.D. · Vanderbilt-Ingram Cancer Center
-
Ingrid Mayer, MD · Vanderbilt-Ingram Cancer Center
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2010-03-31
- Primary Completion
- 2011-07-31
- Completion
- 2011-08-31
Countries
- United States
Study Locations
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