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Thrombus Aspiration in Myocardial Infarction

NCT01093404 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 7243

Last updated 2016-07-11

No results posted yet for this study

Summary

Treatment of myocardial infarction (blood clot in the arteries of the heart) has improved after introduction of 24/7 balloon angioplasty to open the blocked artery. However, the clot itself is not routinely removed but recent data in smaller trials indicate that this might improve recovery and prognosis. In this multicenter study of 5000 patients referred to Scandinavian hospitals for myocardial infarction the investigators test the hypothesis that patients randomized to treatment with thrombus aspiration (removing the blood clot by manual suction) before conventional angioplasty will have a reduced risk of death, fewer rehospitalisations, fewer new myocardial infarctions, reduced risk of heart failure, better coronary artery flow after angioplasty and greater reduction of infarct size compared to patients randomized to conventional angioplasty alone.

Conditions

  • Acute Myocardial Infarction

Interventions

PROCEDURE

Thrombus aspiration

Aspiration of thrombus material before angioplasty

Sponsors & Collaborators

  • Uppsala University

    collaborator OTHER

  • Region Örebro County

    lead OTHER

Principal Investigators

  • Ole Fröbert, MD, PhD · Region Örebro County

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2010-07-31
Primary Completion
2013-03-31
Completion
2013-08-31

Countries

  • Denmark
  • Iceland
  • Sweden

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01093404 on ClinicalTrials.gov