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Predictors of Failed Thrombolysis in Acute Myocardial Infarction

NCT05347732 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 200

Last updated 2023-03-23

No results posted yet for this study

Summary

The purpose of this observational study is to assess why thrombolytic treatment with tissue-plasminogen activator (t-PA) fails in patients with acute ST-segment elevation myocardial infarction (STEMI). The study will include 200 STEMI patients at the time of arrival at Oslo University Hospital Ullevål after receiving prehospital thrombolysis. A blood sample will be taken immediately for the study of factors related to coagulation, fibrinolysis and inflammation. Levels of the biomarkers will be compared between patients with successful and failed thrombolysis.

Conditions

  • STEMI - ST Elevation Myocardial Infarction

Interventions

DIAGNOSTIC_TEST

Successfull thrombolysis

Biomarker levels will be compared between patients with successful and failed thrombolysis.

Sponsors & Collaborators

  • Oslo University Hospital

    lead OTHER

Principal Investigators

  • Ragnhild Helseth, MD PhD · Department of Cardiology, Oslo University Hospital Ullevål

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-04-25
Primary Completion
2025-04-25
Completion
2035-01-03

Countries

  • Norway

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05347732 on ClinicalTrials.gov