Cell-free Circulating DNA in Primary Cutaneous Lymphomas
NCT02883517 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 35
Last updated 2022-05-13
Summary
To evaluate the possibility of detecting cell-free circulating tumoral DNA in potentially aggressive primary cutaneous lymphomas, the investigator opted to search a representative tumor sample mutation in the blood of these patients, by digital PCR. Patients with mycosis fungoides, primary cutaneous T-cell lymphoma helper follicular phenotype and primary cutaneous diffuse large B-cell lymphoma, leg-type will be included and 4 blood samples will be collected during 12 months.
Conditions
- Mycosis Fungoides
- Lymphoma, Large B-cell, Diffuse
Interventions
- GENETIC
-
Cytogenetic and molecular studies
Detect cell-free circulating tumoral DNA in a blood sample, with correlations with clinical characteristics and metastatic outcome.
Sponsors & Collaborators
-
University Hospital, Bordeaux
lead OTHER
Principal Investigators
-
Anne PHAM-LEDARD, MD · University Hospital, Bordeaux
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2016-11-22
- Primary Completion
- 2019-12-16
- Completion
- 2019-12-16
Countries
- France
Study Locations
More Related Trials
-
Studying Genes Associated With Non-Hodgkin Lymphoma in Young Patients
NCT01623856 ·Status: COMPLETED
-
Cell-free Tumor DNA as Minimal Residual Disease in Hodgkin Lymphoma Patients
NCT05254821 ·Status: RECRUITING
-
Feasibility and Clinical Utility of Cell-free DNA (cfDNA) in Identifying Actionable Alterations and Minimal Residual Disease for Lymphoma Patients Across Community Centers in Texas
NCT05676450 ·Status: RECRUITING ·Phase: NA
-
Real-time Monitoring of Concentration and Size Variations of Circulating Plasma Free DNA to Predict Early Response to Immunotherapies in Patients With Different Types of Cancer.
NCT05083494 ·Status: UNKNOWN
-
Fast Track Diagnosis of Skin Cancer by Advanced Imaging Technologies and Tumour Tapestripping
NCT05389085 ·Status: COMPLETED ·Phase: NA
-
Study of DNA Copy Numbers Variations and Gene Expression Profile of Bone Marrow Plasma Cells From MGUS and SMM.
NCT01079429 ·Status: TERMINATED
-
DNA Analysis in Influencing Response to Rituximab in Samples From Patients With Follicular Lymphoma Treated on ECOG-E4402
NCT01406782 ·Status: COMPLETED
-
Studying Tumor Tissue Samples From Patients With Melanoma Who Have Undergone Sentinel Lymph Node Biopsy
NCT00897481 ·Status: UNKNOWN
-
Five Year Study to Track Use of DecisionDX-Melanoma Test in Patients With Cutaneous Melanoma and Associated Patient Outcomes
NCT02355587 ·Status: TERMINATED
-
Early Assessment of Lymphoma Treatment Response Using Phased Variant Analysis With Next-Generation Sequencing
NCT06550427 ·Status: RECRUITING
-
Diagnostic Study of Patients With Aggressive Non-Hodgkin's Lymphoma
NCT00003863 ·Status: COMPLETED
-
Study of Circulating Tumoral DNA in Metastatic Choroidal Melanoma
NCT01334008 ·Status: COMPLETED ·Phase: NA
-
Establishing a Tumor Bank in Families With Multiple Lymphoproliferative Malignancies
NCT00131014 ·Status: RECRUITING
-
Skin Tumor Biomarkers by Mass Spectrometry Imaging
NCT06227416 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Circulating Cell-free DNA in Metastatic Melanoma Patient: Mutational Analyses in Consecutive Measurement Before and After Chemotherapy
NCT02133222 ·Status: COMPLETED ·Phase: NA
-
Familial Investigations of Childhood Cancer Predisposition
NCT03050268 ·Status: RECRUITING
-
Natural History Study of Moles and Suspicious Melanoma
NCT00288938 ·Status: COMPLETED
-
Long Term Follow-Up of Patients on Children's Cancer Group Protocols- (CCG-LTF1) FOLLOW-UP DATA
NCT00588289 ·Status: COMPLETED
-
Tumor Cell and DNA Detection in the Blood, Urine and Bone Marrow of Patients With Solid Cancers
NCT02838836 ·Status: RECRUITING
-
Detection of Melanoma Markers in Lymph Nodes or Peripheral Blood of Patients With Melanoma
NCT00004153 ·Status: COMPLETED ·Phase: NA
-
Study of MGUS, Smoldering Myeloma, Early MDS and CLL to Assess Molecular Events of Progression and Clinical Outcome
NCT02269592 ·Status: RECRUITING
-
Skin Barrier and Microbiome of CTCL Patients
NCT05827107 ·Status: COMPLETED
-
Feasibility Study of a Molecular Karyotype Using a Very High-throughput Sequencing Approach, the "Massive Parallel Sequencing" on Circulating Tumor DNA
NCT04104633 ·Status: COMPLETED ·Phase: NA
-
Biomarkers in Predicting Response to Rituximab Treatment in Samples From Patients With Indolent Follicular Lymphoma
NCT01381705 ·Status: COMPLETED
-
A Study of Circulating Tumor DNA (ctDNA) Testing for People With B-Cell Lymphoma
NCT06736613 ·Status: RECRUITING ·Phase: PHASE2