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Folic Acid and Creatine as Therapeutic Approaches for Lowering Blood Arsenic

NCT01050556 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 600

Last updated 2012-08-01

No results posted yet for this study

Summary

The purpose of this study is to determine whether folic acid, alone or together with creatine supplementation, can lower blood arsenic concentrations and improve the ability to detoxify arsenic.

Conditions

  • High Blood Arsenic Due to Chronic Arsenic Exposure

Interventions

OTHER

Placebo

daily, 24 weeks

DIETARY_SUPPLEMENT

folic acid

400 ug/d for 12 or 24 weeks

DIETARY_SUPPLEMENT

folic acid

800 µg/d for 12 or 24 weeks

DIETARY_SUPPLEMENT

creatine

3 mg/d for 12 weeks

DIETARY_SUPPLEMENT

creatine + folic acid

3 mg creatine/d + 400 µg folic acid/d for 12 weeks

Sponsors & Collaborators

Principal Investigators

  • Mary V Gamble, PhD · Columbia University, Department of Environmental Health Sciences

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
20 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2010-09-30
Primary Completion
2011-06-30
Completion
2011-06-30

Countries

  • Bangladesh

Study Locations

More Related Trials

Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01050556 on ClinicalTrials.gov