Advanced Gastrointestinal Endoscopic Imaging

Summary

To develop new methods to detect malignant and premalignant conditions of the gastrointestinal tract.

Conditions

• Gastrointestinal Diseases
• Gastric (Stomach) Cancer
• Gastrointestinal Stromal Tumor (GIST)

Interventions

DEVICE

Dual axis endoscopic microscope

This is a device that is used in the accessory port of a standard endoscope and allows visualization of microscopic areas of mucosa.

DEVICE

wide field fluorescence system

This is a modification to the existing narrow band endoscope from Olympus that incorporates different filters on the source and collecting optics to enable fluorescence imaging. It is used as is a standard endoscope.

DEVICE

CellVizio

Minimicroscope--this is an FDA approved fiber-based microscope that we will use according to the manufacturers protocols.

DRUG

fluorescent Peptide

microdosing; Topical through the endoscope

DRUG

fluorescein

100 mcg topical

DRUG

indocyanine green

100 mcg topical

Sponsors & Collaborators

• National Institutes of Health (NIH)

  collaborator NIH

• National Cancer Institute (NCI)

  collaborator NIH

• Stanford University

  lead OTHER

Principal Investigators

• Shai Friedland · Stanford University

Study Design

Allocation

NA

Purpose

DIAGNOSTIC

Masking

NONE

Model

SINGLE_GROUP

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2009-06-30

Primary Completion

2017-09-25

Completion

2017-09-25

Countries

• United States

Study Locations