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Narrow Band Imaging for Gastric Neoplasia

NCT02197351 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 220

Last updated 2023-03-06

No results posted yet for this study

Summary

It is thought that the development of cancer of the stomach follows a series of stages in which the lining becomes increasingly abnormal. Early detection of precursors of gastric cancer likely enable less invasive treatment.

The assessment of gastric mucosa using the endoscope is used to detect cancers and these precursor lesions. Narrow band imaging uses filtered light already built into modern endoscopoes to identify the early changes in the gastric lining.

The investigators' hypothesis is that narrow band imaging improves detection of precursor lesions and is a method amenable to international standardization.

The investigators will conduct a prospective trial in which standard random biopsy, white light guided biopsy, and narrow band imaging guided biopsy will be performed for each patient. The yield of the different methods for gastric cancer precursors will thus be compared.

Conditions

Interventions

PROCEDURE

White light biopsy

Endoscopy with biopsies guided by high definition white light

PROCEDURE

Protocolled

Upper Endoscopy with Protocolled Biopsy (i.e. biopsy by predetermined guideline not influenced by white light or narrow band imaging findings)

PROCEDURE

Narrow Band Imaging Guided Biopsy

Upper Endoscopy with biopsy guided by narrow and imaging

Sponsors & Collaborators

  • Universidade do Porto

    collaborator OTHER

  • University of Southern California

    lead OTHER

Principal Investigators

  • James Buxbaum, MD · University of Southern California

Study Design

Allocation
NA
Purpose
DIAGNOSTIC
Masking
SINGLE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2014-07-31
Primary Completion
2023-12-31
Completion
2023-12-31

Countries

  • United States
  • Portugal

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02197351 on ClinicalTrials.gov