PROMOTE: Promotion of the Mind Through Exercise

Summary

The investigators will conduct a proof-of-concept study to provide preliminary evidence of efficacy of aerobic-based exercise training for maintaining cognitive function, executive function, and everyday function in adults with mild vascular cognitive impairment.

Conditions

• Vascular Cognitive Impairment

Interventions

BEHAVIORAL

Aerobic-based exercise training

Six months of thrice-weekly walking program that will gradually progress in intensity. Each training session will be 60 minutes (10 minutes of warm-up, 40 minutes of training, and 10 minutes of cool-down).

BEHAVIORAL

CON (control; usual care)

Nutrition education and usual care as prescribed by neurologist

Sponsors & Collaborators

• Canadian Stroke Network

  collaborator OTHER

• Heart and Stroke Foundation of Canada

  collaborator OTHER

• University of British Columbia

  lead OTHER

Principal Investigators

• Teresa Liu-Ambrose, Ph.D, PT · University of British Columbia

• Janice Eng, Ph.D · University of British Columbia

• Lara Boyd, Ph.D · University of British Columbia

• Robin Hsiung, Ph.D · University of British Columbia

• Claudia Jacova, Ph.D · University of British Columbia

• Howard Feldman, MD · University of British Columbia

• Penny Brasher, Ph.D · University of British Columbia

• Philip Lee, Ph.D · University of British Columbia

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Model

SINGLE_GROUP

Eligibility

Min Age

45 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2009-12-31

Primary Completion

2014-12-31

Completion

2015-05-31

Countries

• Canada

Study Locations