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Physical Exercise to Prevent Mild-cognitive Impairment in Patients With Kidney Disfunctions

NCT07160959 · Status: NOT_YET_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 124

Last updated 2025-09-08

No results posted yet for this study

Summary

This research project focuses on improving memory and thinking (cognitive function) in people with advanced chronic kidney disease (CKD), a condition that affects about 10% of adults and is often linked to cognitive problems. The study includes a clinical trial where patients will either receive standard care or follow a home-based exercise program involving walking and strength training, to see if regular physical activity can improve brain function. It also includes a large-scale analysis of data from the UK Biobank to explore blood and genetic markers, brain imaging, and lifestyle factors linked to cognitive health. The ultimate aim is to find effective, easy-to-implement strategies and early warning signs that could lead to better treatment and quality of life for people living with CKD.

Conditions

  • Chronic Kidney Disease (Stages 4 and 5)
  • Mild Cognitive Impairment (MCI)

Interventions

BEHAVIORAL

Exercise

Patients will undergo a home-based low-intensity interval multi component exercise program including aerobic and strengthening exercise

OTHER

Control (Standard treatment)

Patients will be treated with standard therapy based on their CKD stage

Sponsors & Collaborators

  • Biogem s.c.ar.l.

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-01-01
Primary Completion
2028-04-30
Completion
2030-04-30

Countries

  • France
  • Italy
  • Lithuania
  • Netherlands
  • Poland
  • Switzerland

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07160959 on ClinicalTrials.gov