MedTrace Logo

Combined Nutritional and Exercise Strategies to Reduce Liver Fat Content in Patients With Type 2 Diabetes

NCT01025856 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 45

Last updated 2012-12-05

No results posted yet for this study

Summary

The aim of this study will be to evaluate in patients with type 2 diabetes the effects on liver fat of an intervention with a diet relatively rich in CHO/rich in fibre/low GI or a diet rich in MUFA, either combined or not with a structured program of physical exercise, with emphasis on mechanisms possibly underlining these effects, namely changes in postprandial triglyceride-rich lipoproteins, body fat distribution, insulin sensitivity, oxidative stress and inflammation, adipose tissue lipolytic activities, aerobic capacity and endothelial function.

Conditions

Interventions

OTHER

Rich in MUFA diet -PA

The patients will follow a rich in MUFA diet without a physical activity program.

OTHER

high fiber/low glycemic index diet + pa

patients will follow for two months a high fibre/ low glycemic index diet with a physical activity program.

OTHER

Rich in MUFA diet+PA

Patients will follow for two months a rich in MUFA diet with a physical activity program.

OTHER

High fibre/low glycemic index diet-PA

Patients will follow for two months a high fibre/low glycemic index diet without a physical activity program.

Sponsors & Collaborators

  • Federico II University

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
35 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2009-09-30
Primary Completion
2011-09-30
Completion
2011-09-30

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01025856 on ClinicalTrials.gov