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Terlipressin in Septic Shock: Effects on Microcirculation

NCT00995839 · Status: COMPLETED · Phase: PHASE2/PHASE3 · Type: INTERVENTIONAL · Enrollment: 60

Last updated 2010-02-04

No results posted yet for this study

Summary

The present study was conducted as a prospective, randomized study to investigate the effects of vasopressin receptor agonists terlipressin and vasopressin on systemic hemodynamics and microcirculation in patients with catecholamine-dependent septic shock.

Conditions

Interventions

DRUG

continuous infusion of terlipressin

Intravenous continuous infusion of terlipressin 1 µg•kg-1•h-1 for 6 hrs

DRUG

Arginine vasopressin

Intravenous continuous infusion of arginine vasopressin 0.04 UI•min-1 for 6 hrs

DRUG

terlipressin bolus administration

intravenous terlipressin bolus administration at the dose of 0.5 mg

Sponsors & Collaborators

  • University of Roma La Sapienza

    lead OTHER

Principal Investigators

  • Andrea Morelli, MD · University of Rome "La Sapienza", Department of Anesthesiology and Intensive Care

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2008-11-30
Primary Completion
2010-02-28
Completion
2010-02-28

Countries

  • Italy

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00995839 on ClinicalTrials.gov