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Hypotension in the Weaning From Vasopressor Drugs

NCT05506319 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 78

Last updated 2025-03-14

No results posted yet for this study

Summary

Although there is consensus in the literature on hemodynamic management of septic shock in the resuscitation phase, the best way to conduct the weaning of vasopressor drugs in the stabilization phase remains open. The present study aims to study the incidence of hypotension in the weaning phase of vasopressor drugs- norepinephrine and vasopressin.

Conditions

  • Septic Shock

Interventions

OTHER

Norepinephrine

The patients will be randomized for the initial suspension of norepinephrine (norepinephrine group).

OTHER

Vasopressin

The patients will be randomized for the initial suspension of vasopressin (vasopressin group).

Sponsors & Collaborators

  • Hospital Nossa Senhora da Conceicao

    lead OTHER

Principal Investigators

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-05-01
Primary Completion
2022-12-01
Completion
2023-06-30

Countries

  • Brazil

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05506319 on ClinicalTrials.gov