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Functional Imaging of Tumor and Normal Tissue

NCT00933114 · Status: TERMINATED · Type: OBSERVATIONAL · Enrollment: 21

Last updated 2012-04-11

No results posted yet for this study

Summary

Dynamic contrast-enhanced (DCE) - magnetic resonance imaging (MRI), diffusion-weighted (DW)-MRI, and fludeoxyglucose - positron emission tomography - computed tomography (FDG-PET-CT) are three modalities that generate non-invasive, functional images of tumors and normal tissues based on physiologic properties including perfusion, vascular permeability and glucose metabolism. Demonstrating that these parameters are associated with clinical outcome, either efficacy or toxicity, could enhance the ability to select patients for different treatment strategies and improve the therapeutic ratio.

Conditions

Interventions

PROCEDURE

MRI and PET imaging

Dynamic Enhanced Magnetic Resonance Imaging (DEC-MRI) and positron emission tomography (PET) scan at baseline and after 1 week of radiation therapy

Sponsors & Collaborators

Principal Investigators

  • David S Yoo, MD, PhD · Duke University Medical Center, Dept Radiation Oncology

  • David M Brizel, MD · Duke University Medical Center Dept Radiation Oncology

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2009-10-31
Primary Completion
2011-09-30
Completion
2011-09-30

Countries

  • United States

Study Locations

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Entities

Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00933114 on ClinicalTrials.gov