Safety and Tolerability of Coenzyme Q10 in Hemodialysis Patients
NCT00908297 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 20
Last updated 2012-04-24
Summary
The purpose of this study is to determine the safety and tolerability of the dietary supplement Coenzyme Q10 in hemodialysis patients.
Conditions
- Cardiovascular Disease
- End Stage Renal Disease
- Atherosclerosis
- Oxidative Stress
Interventions
- DIETARY_SUPPLEMENT
-
Coenzyme Q10
By mouth (wafer) once daily for duration of study (8 weeks). Dose escalation: * 300 mg for two weeks * 600 mg for two weeks * 1200 mg for two weeks * 1800 mg for final two weeks
Sponsors & Collaborators
-
National Center for Complementary and Integrative Health (NCCIH)
collaborator NIH - lead OTHER
Principal Investigators
-
Jonathan Himmelfarb, MD · University of Washington - Kidney Research Institute
Study Design
- Allocation
- NA
- Purpose
- PREVENTION
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 85 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2010-02-28
- Primary Completion
- 2010-10-31
- Completion
- 2010-11-30
Countries
- United States
Study Locations
More Related Trials
-
Clearance of 25-hydroxyvitamin D in Chronic Kidney Disease
NCT02937350 ·Status: COMPLETED ·Phase: PHASE1
-
Effect of 25-hydroxyvitamin D and a Structured Exercise Program on Dialysis Patients
NCT00798993 ·Status: COMPLETED ·Phase: PHASE4
-
Isoflavones and Acute-phase Response in Chronic Renal Failure
NCT00029796 ·Status: COMPLETED ·Phase: PHASE2
-
Immune Effects of Vitamin D in Hemodialysis Patients
NCT00686751 ·Status: COMPLETED ·Phase: PHASE2
-
Impact of Vitamin D Therapies on Chronic Kidney Disease
NCT01222234 ·Status: COMPLETED ·Phase: NA
-
Vitamin D, Oxidative Stress and Inflammation in Hemodialysis
NCT05460338 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Impact of Vitamin D on Endothelial Function and Blood Biomarkers Including CD28 Null Cells in CKD
NCT02005718 ·Status: COMPLETED ·Phase: PHASE3
-
A Novel Role of Alpha Lipoic Acid in Comparison With Selenium in Mitochondrial Resuscitation and miRNA-126 Expression in Hemodialysis Patients
NCT05266794 ·Status: COMPLETED ·Phase: PHASE4
-
Safety and Effects of Supplementation With Ergocalciferol on Erythropoietin Dosing in Hemodialysis Patients
NCT01395823 ·Status: COMPLETED ·Phase: PHASE4
-
Supplemented Low Protein Diet and Progression of CKD
NCT03818568 ·Status: COMPLETED ·Phase: NA
-
Repletion of Ergothioneine in Patients With Kidney Failure
NCT06487546 ·Status: RECRUITING ·Phase: NA
-
Vitamin D Supplement Study for Stage Three and Four Chronic Kidney Disease (CKD) Patients
NCT01173848 ·Status: TERMINATED ·Phase: PHASE3
-
Palm Tocotrienols in Chronic Hemodialysis (USA)
NCT02358967 ·Status: COMPLETED ·Phase: NA
-
Differential Effects of Ergocalciferol and Cholecalciferol Therapies in Chronic Kidney Disease
NCT01835691 ·Status: COMPLETED ·Phase: NA
-
Effect of a Specialized Oral Supplement on Nutritional Status and Quality of Life in Non-dialysis CKD
NCT06576479 ·Status: RECRUITING ·Phase: NA
-
Gut Microbiome and p-Inulin in Hemodialysis
NCT02572882 ·Status: COMPLETED ·Phase: NA
-
Effect of Vitamin D3 Supplementation on Arterial and Bone Remodeling in Chronic Kidney Disease Patients
NCT02999204 ·Status: COMPLETED ·Phase: PHASE4
-
Mitochondria and Chronic Kidney Disease
NCT03177798 ·Status: COMPLETED ·Phase: PHASE2
-
Omega 3 Fatty Acids in Patients With Chronic Renal Disease
NCT03280615 ·Status: COMPLETED ·Phase: PHASE3
-
Exploring the Mechanisms of Indoxyl Sulfate Production by Oral Tryptophan Challenge Test
NCT04117191 ·Status: COMPLETED ·Phase: NA
-
How Vitamin D Analogues Affect Endothelial Cells in Patients on Dialysis
NCT00528788 ·Status: COMPLETED ·Phase: PHASE4
-
Effects of Fhytomenadione on Coronary Artery Calcification of Hemodialysis Patients
NCT04247087 ·Status: COMPLETED ·Phase: NA
-
Tocopherols and Alpha Lipoic Acid Treatment Chronic Kidney Disease (TALAT)
NCT00308971 ·Status: COMPLETED ·Phase: PHASE2
-
Vitamin D Effect on Calcium Absorption on Persons on Hemodialysis
NCT01325610 ·Status: COMPLETED ·Phase: NA
-
Effect of Sevelamer Carbonate on Oxidative Stress in Patients With Diabetic Nephropathy
NCT00967629 ·Status: COMPLETED ·Phase: PHASE1