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A Study to Investigate the Efficacy and Safety of Different Doses of Losartan Potassium (MK0954-011)

NCT00882440 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 576

Last updated 2015-08-27

Study results available
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Summary

The purpose of this study was to compare the antihypertensive efficacy of different doses of losartan compared to placebo and enalapril, in patients with supine diastolic blood pressure of 100-115 mmHg.

Conditions

Interventions

DRUG

losartan potassium

losartan oral capsule (10, 25, 50, 100 or 150 mg) once daily for 8 weeks

DRUG

Placebo

Placebo capsule to losartan

DRUG

Enalapril

Enalapril 20 mg oral tablet taken once daily for 8 weeks

Sponsors & Collaborators

Principal Investigators

  • Medical Monitor · Merck Sharp & Dohme LLC

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
21 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
1990-12-31
Primary Completion
1991-08-31
Completion
1992-01-31

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00882440 on ClinicalTrials.gov