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AVE7688 in Patients With Mild to Moderate Blood Pressure

NCT00284128 · Status: COMPLETED · Phase: PHASE2/PHASE3 · Type: INTERVENTIONAL · Enrollment: 1940

Last updated 2016-05-18

No results posted yet for this study

Summary

The primary objective is to assess the antihypertensive efficacy of 4 different AVE 7688 doses on the change from baseline in trough diastolic blood pressure at the end of week 12.

The secondary objectives are:

* To assess the antihypertensive efficacy of 4 different AVE 7688 doses on the change from baseline in trough systolic blood pressure at the end of week 12
* To compare the percentages of responders after 12 week of treatment
* To evaluate the long term safety and tolerability of AVE 7688 with particular attention to angioedema

Conditions

Interventions

DRUG

AVE7688

oral administration (capsules)

DRUG

Losartan-potassium

oral administration (capsules)

Sponsors & Collaborators

Principal Investigators

  • Clinical Sciences & Operations · Sanofi

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2005-12-31
Primary Completion
2008-03-31
Completion
2008-03-31

Countries

  • United States
  • Argentina
  • Brazil
  • Canada
  • Chile
  • Germany
  • Greece
  • Hong Kong
  • Italy
  • Malaysia
  • Mexico
  • Netherlands
  • Poland
  • Portugal
  • Russia
  • Singapore
  • South Africa
  • South Korea
  • Spain
  • Taiwan
  • Turkey (Türkiye)

Study Locations

More Related Trials

Entities

Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00284128 on ClinicalTrials.gov