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Associations Between Depression and Cardiovascular Disease - a Study of Patients With Late Onset Depression

NCT00818506 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 55

Last updated 2012-11-21

No results posted yet for this study

Summary

Studies show that depression is a risk factor for the development of coronary artery disease (CAD). Furthermore there is an increased occurrence of depression in patients with CAD. Among other mechanisms atherosclerosis is believed to play a central role regarding these notable associations between depression and CAD. Moreover, patients with late onset major depression have an increased number of small lesions found in the white matter of the brain, the so-called white matter lesions. The main goal of this project is to examine if CAD is associated with depression and/or white matter lesions. CAD is evaluated using coronary CT angiography. Depression is evaluated using a semi-structured diagnostic interview. White matter lesions are quantified using cerebral magnetic resonance.

Conditions

Sponsors & Collaborators

  • The Ministry of Science, Technology and Innovation, Denmark

    collaborator OTHER_GOV

  • Vejle Hospital

    collaborator OTHER

  • Danish National Research Foundation

    collaborator OTHER

  • Aarhus University Hospital

    collaborator OTHER

  • Augustinus Fonden

    collaborator OTHER

  • University of Aarhus

    lead OTHER

Principal Investigators

  • Poul Videbech, Professor, M.D., Dr.Med. · Center of Psychiatric Research, Aarhus University Hospital

Eligibility

Min Age
50 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2009-03-31
Completion
2012-06-30

Countries

  • Denmark

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00818506 on ClinicalTrials.gov