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Cardiac Markers in Depressed Patients With Coronary Heart Disease - R01HL147862

NCT04682769 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 175

Last updated 2025-12-24

No results posted yet for this study

Summary

Depression doubles the risk of death in patients with coronary heart disease (CHD), but so far, there is insufficient evidence that we can reduce the risk of death by treating depression. This study will investigate the cardiac risk markers that are associated with depression symptoms that remain despite treatment, and identify potential targets for their treatment. The results of the study will inform the development of more effective interventions to improve both depression and survival in patients with CHD.

Conditions

Interventions

OTHER

Other

Patients with Coronary Heart Disease and Depressive Disorder are receiving routine treatment by their physician.

Sponsors & Collaborators

  • Washington University School of Medicine

    lead OTHER

Principal Investigators

  • Kenneth E Freedland, PhD · Washington University School of Medicine

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-12-01
Primary Completion
2025-01-25
Completion
2025-05-31

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04682769 on ClinicalTrials.gov