Biomarkers of Antidepressant Response and Suicidal Events in Depressed Youth
NCT03547219 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 152
Last updated 2019-04-04
Summary
The aims of this study are to (1) identify inflammatory/neurotrophic and neurodevelopmental markers that predict antidepressant response and suicidal risk in depressed youth and (2) predict their treatment response and the occurrence of suicidal events at the individual level using machine learning approach.
Conditions
- Depression
- Adolescent
Interventions
- DRUG
-
Escitalopram
Sponsors & Collaborators
-
National Research Foundation of Korea
collaborator OTHER -
Seoul National University
lead OTHER
Principal Investigators
-
Jae-Won Kim, MD, PhD · Seoul National University and Seoul National University Hospital
Study Design
- Allocation
- NA
- Purpose
- BASIC_SCIENCE
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 12 Years
- Max Age
- 17 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2015-08-05
- Primary Completion
- 2018-08-02
- Completion
- 2018-08-02
Countries
- South Korea
Study Locations
More Related Trials
-
Serotonergic Modulation of Cognition, Emotion and Brain Activation in Healthy Volunteers
NCT04239339 ·Status: COMPLETED ·Phase: PHASE4
-
Efficacy and Safety of SR58611A in Patients With Major Depressive Disorder
NCT00252330 ·Status: COMPLETED ·Phase: PHASE3
-
Development of Escitalopram Genomic Device by Using Candidate Gene Approach and Genome-Wide Scanning
NCT00935246 ·Status: UNKNOWN ·Phase: NA
-
The Effects of Escitalopram on Cytokines
NCT01587326 ·Status: UNKNOWN ·Phase: NA
-
A Study to Evaluate the Impact of Escitalopram on Quality of Life and Social Functionality in Patients With Major Depressive Disorder With Anxiety Symptom
NCT01870843 ·Status: COMPLETED ·Phase: PHASE4
-
A Safety and Efficacy Study of Escitalopram on Acute Treatment of Severe Depression
NCT01814085 ·Status: COMPLETED ·Phase: PHASE4
-
Mechanisms of Antidepressant Non-Response in Late-Life Depression
NCT01931202 ·Status: COMPLETED ·Phase: NA
-
Efficacy and Safety of Escitalopram Doses up to 50mg in Treatment of MDD
NCT00785434 ·Status: COMPLETED ·Phase: PHASE4
-
Brain Energy Metabolism in Individuals With Major Depressive Disorder Receiving Escitalopram
NCT00183677 ·Status: COMPLETED ·Phase: PHASE4
-
A Clinical Trial to Investigate the Pharmacokinetics and the Effect on ECG of Escitalopram in Elderly Volunteers
NCT02122939 ·Status: COMPLETED ·Phase: PHASE1
-
Escitalopram in Depressive Patients With Acute Coronary Artery Syndrome
NCT00419471 ·Status: COMPLETED ·Phase: PHASE4
-
Study of Electrophysiological Markers of Antidepressants in Major Depressive Disorder
NCT06532604 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
A Neuroimaging and Epigenetic Investigation of Antidepressants in Depression
NCT00703742 ·Status: COMPLETED ·Phase: NA
-
Comparison of Escitalopram Combination in Adult Patients With Major Depressive Disorder
NCT00109044 ·Status: COMPLETED ·Phase: PHASE3
-
Safety Study of Escitalopram in Children 7 to 11 Years of Age With Major Depressive Disorder
NCT01198795 ·Status: COMPLETED ·Phase: PHASE4
-
Lexapro®'s Efficacy After Dose Escalation in Remission Study
NCT01594866 ·Status: COMPLETED ·Phase: PHASE4
-
Study of Escitalopram in Adult Patients With Major Depressive Disorder
NCT00108979 ·Status: COMPLETED ·Phase: PHASE3
-
The Safety and Efficacy of Escitalopram in Pediatric Patients With Major Depressive Disorder
NCT00107120 ·Status: COMPLETED ·Phase: PHASE3
-
An Efficacy and Safety Study of Escitalopram Long-Term Treatment in Major Depressive Disorder With Associated Anxiety Symptoms
NCT01814098 ·Status: COMPLETED ·Phase: PHASE4
-
The Effect of Escitalopram on Mood, Quality of Life and Cognitive Functioning in Glioblastoma Patients
NCT02623231 ·Status: UNKNOWN ·Phase: PHASE2/PHASE3
-
Brain Activity Changes and Treatment Response in Depressed People Who Are Receiving Antidepressant Medication
NCT00375843 ·Status: COMPLETED ·Phase: PHASE4
-
Leveraging EEG for Antidepressant Prediction With Sertraline and Escitalopram
NCT04388202 ·Status: WITHDRAWN ·Phase: PHASE4
-
Study to Evaluate the Efficacy, Safety and Tolerability of Bupropion Hydrochloride Extended-release Tablet, and Escitalopram Oxalate Capsule in Subjects With Major Depressive Disorder
NCT02191397 ·Status: COMPLETED ·Phase: PHASE3
-
Serotonin Transporter Genetic Variation and Amygdalar Activation Correlates of Antidepressant Response
NCT00456430 ·Status: COMPLETED ·Phase: PHASE4
-
Escitalopram in the Treatment of Dysthymic Disorder, Double Blind
NCT00220701 ·Status: COMPLETED ·Phase: PHASE4