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Arterial Blood Pressure-complexity in Septic Patients

NCT00793078 · Status: SUSPENDED · Type: OBSERVATIONAL · Enrollment: 72

Last updated 2011-03-01

No results posted yet for this study

Summary

Arterial blood pressure (ABP) is regulated by multiple, interconnected feedback loops resulting in a variable and complex time course. According to the "decomplexification theory of illness", disease is characterised by a loss or impaired function of feedback loops resulting in a decreased complexity of the ABP-time course and an impaired adaptability of the cardiovascular system.

Decomplexification of physiologic parameters has been shown to occur in coronary heart disease, Parkinson's and Hodgkin's disease, and in subarachnoid hemorrhage, but has not been evaluated in sepsis.

This study is intended to test the hypothesis that complexity of ABP

* is lower in cardiac surgery versus non-cardiac surgery septic patients,
* decreases as severity of sepsis increases to severe sepsis and septic shock,
* is associated with outcome three month after sepsis.

Conditions

Sponsors & Collaborators

  • University Hospital, Bonn

    lead OTHER

Principal Investigators

  • Martin Soehle, M.D., D.E.S.A., D. habil. · Dept. of Anaesthesiology and Intensive Care Medicine, University of Bonn

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2009-01-31
Primary Completion
2012-12-31
Completion
2012-12-31

Countries

  • Germany

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00793078 on ClinicalTrials.gov