Surveillance of Influenza Virus Among Children With Febrile Respiratory Complaints Attending the Pediatric Clinic of the First Affiliated Hospital, Shantou University Medical College, Shantou, Guangdong, Mainland China
NCT00760500 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 13201
Last updated 2015-02-18
Summary
The surveillance of influenza virus among children with febrile reparatory complaints attending the pediatric clinic in Shantou is an epidemiologic study to identify the type (influenza A or B) and the subtype of Influenza A of the isolates from children with febrile respiratory complaints who attend the pediatric clinic of the first Affiliated Hospital, Shantou University Medical College, Shantou Guangdong, China. Also this study investigates the genetic composition of all segments of isolated strains using standard molecular techniques and to make available the new strains of influenza viruses isolated from such children for the formulation of influenza vaccines. Clinical manifestation of the respiratory illness is recorded and single nasopharyngeal swab is obtained from eligible children. Viral culture is performed on the nasopharyngeal secretions. If influenza is isolated, this is characterized if it belongs to influenza A or B. If the virus is characterized as influenza A, further antigenic studies is done to determine subtype of influenza. Viral isolates is further studied to determine the genetic composition of the virus. Information obtained from the viral isolates is shared with the WHO and the CDC.
Conditions
- Influenza Type A
- Influenza Type B
Interventions
- OTHER
-
Nasopharyngeal Swab
Nasopharyngeal Swab
Sponsors & Collaborators
-
The University of Hong Kong
collaborator OTHER -
National Institute of Allergy and Infectious Diseases (NIAID)
collaborator NIH -
St. Jude Children's Research Hospital
lead OTHER
Principal Investigators
-
Miguela Caniza, MD · St. Jude Children's Research Hospital
Eligibility
- Max Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2004-01-31
- Primary Completion
- 2014-03-31
- Completion
- 2014-03-31
Countries
- China
Study Locations
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