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Direct and Indirect Benefits of Influenza Vaccine Versus Placebo in Healthy Children

NCT00792051 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 2800

Last updated 2014-12-30

No results posted yet for this study

Summary

While immunisation of school-age children against influenza is not recommended in Hong Kong, past experience in Japan and elsewhere suggests that immunisation of children may protect the wider community through its indirect transmission-limiting impact as well as the direct immunologic protection afforded vaccinated children themselves. We aim to assess whether vaccinating children against influenza protects vaccinees as well as their household contacts from infection.

Conditions

  • Influenza Virus Infection

Interventions

BIOLOGICAL

Inactivated influenza vaccine

0.5ml intramuscular single dose

BIOLOGICAL

Saline

0.5ml intramuscular, one dose

Sponsors & Collaborators

  • Research Fund for the Control of Infectious Diseases

    collaborator UNKNOWN

  • Research Grants Council, Hong Kong

    collaborator OTHER

  • Centre for Health Protection, Hong Kong

    collaborator OTHER_GOV

  • The University of Hong Kong

    lead OTHER

Principal Investigators

  • Benjamin J Cowling, PhD · The University of Hong Kong

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
TRIPLE
Model
PARALLEL

Eligibility

Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2008-09-30
Primary Completion
2010-12-31
Completion
2010-12-31

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00792051 on ClinicalTrials.gov