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Aldosterone and Glucose Homeostasis

NCT00732160 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 34

Last updated 2017-04-06

Study results available
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Summary

Determine the effect of aldosterone on how the body handles glucose (sugar).

Conditions

Interventions

DRUG

Aldosterone infusion (A)

Infusion of exogenous aldosterone (0.7 mcg/kg/hr for 12.5 hrs)

DRUG

Vehicle Infusion (V)

Vehicle infusion for 12.5 hours

OTHER

High Sodium Diet (HS)

160 mmol/d sodium diet for 7 days

OTHER

Low Sodium Diet (LS)

20 mmol/d sodium diet for 9 days

Sponsors & Collaborators

  • National Heart, Lung, and Blood Institute (NHLBI)

    collaborator NIH

  • National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

    collaborator NIH

  • Vanderbilt University

    lead OTHER

Principal Investigators

  • James M Luther, MD · Vanderbilt University Medical Center

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
QUADRUPLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2008-09-30
Primary Completion
2012-09-30
Completion
2013-12-31

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00732160 on ClinicalTrials.gov