Effect of Aldosterone Blockade on Arterial Compliance
NCT01089309 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 51
Last updated 2010-03-29
Summary
The present study investigated the long-term (12 months) effect of spironolactone treatment on glucose homeostasis, metabolic parameters and vascular properties.
Conditions
- Arterial Stiffness
- Arterial Elasticity
Interventions
- DRUG
-
Spironolactone
Spironolactone orally, at a dose of 50 mg/day for 12 months
Sponsors & Collaborators
-
Wolfson Medical Center
lead OTHER_GOV
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- SINGLE
- Model
- PARALLEL
Eligibility
- Min Age
- 45 Years
- Max Age
- 85 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2004-05-31
- Primary Completion
- 2007-06-30
- Completion
- 2007-06-30
Countries
- Israel
Study Locations
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