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Role of Leukotrienes and Adenosine in Hyperpnea-induced Bronchospasm

NCT00710255 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 8

Last updated 2016-10-31

No results posted yet for this study

Summary

This research is being conducted to help us better understand what causes exercise induced asthma. The investigators hypothesize that two types of chemicals, cysteinyl leukotrienes and adenosine, play an important role. The investigators will be measuring these chemicals in the exhaled breath of volunteers with exercise induced asthma as they undergo a test to mimic exercise induced asthma. The investigators will determine how the levels of these chemicals change in association with how lung function changes before, during and after an episode of exercise induced asthma.

Conditions

  • Asthma, Exercise Induced

Interventions

PROCEDURE

Hyperpnea challenge

5 minutes of dry air hyperpnea to induce bronchospasm

Sponsors & Collaborators

  • University of Vermont

    lead OTHER

Principal Investigators

  • David A. Kaminsky, MD · University of Vermont

Eligibility

Min Age
12 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2007-10-31
Primary Completion
2009-03-31
Completion
2009-07-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00710255 on ClinicalTrials.gov