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Lactobacillus Plantarum 299v in Colon Surgery

NCT00695461 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 72

Last updated 2008-06-11

No results posted yet for this study

Summary

Intestinal pathogenes are often involved in postoperative complications after colon surgery. Probiotic bacteria, i e live bacteria which have beneficial effects on the host when ingested, have been shown to reduce bacterial translocation in animal studies. However, in humans studies results have varied. The purpose with this study was to find whether high doses of Lactobacillus plantarum 299v affects the potentially pathogenic microflora of the gut, bacterial translocation and cell proliferation in patients undergoing planned colon surgery.

Conditions

Interventions

DIETARY_SUPPLEMENT

Lactobacillus plantarum 299v in oatmeal drink

Bacteria in a concentration of 10(9) CFU/ml

DIETARY_SUPPLEMENT

Oatmeal drink

Oatmeal drink as in arm 1 but without bacteria added.

Sponsors & Collaborators

  • Skane University Hospital

    lead OTHER

Principal Investigators

  • Peter Mangell, MD · Dept of Surgery, Malmö University Hospital, Malmö, Sweden

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2001-01-31
Primary Completion
2004-06-30
Completion
2006-08-31

Countries

  • Sweden

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00695461 on ClinicalTrials.gov