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Effect of Probiotics on Oral Wound Healing - Pilot Study

NCT03210779 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 10

Last updated 2018-05-22

No results posted yet for this study

Summary

This research will study the healing of standardized wounds created in the oral mucosa of volunteer participants during daily intake of tablets and topical application of oil containing the probiotic bacterium Lactobacillus reuteri. Our null hypothesis is that the consumption and topical application of probiotic supplements containing L. reuteri does not improve clinical healing of oral wounds in healthy participants when compared to controls.

Conditions

  • Wound

Interventions

DIETARY_SUPPLEMENT

L. reuteri DSM 17938/ATCC PTA

Ingestion of active lozenge twice daily for 16 days and topical application of active oil once daily for 8 days

DIETARY_SUPPLEMENT

Placebo

Ingestion of inactive lozenge twice daily for 16 days application of inactive oil once daily for 8 days

Sponsors & Collaborators

Principal Investigators

  • Svante Twetman, PhD · University of Copenhagen

Study Design

Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
DOUBLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
50 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2016-12-05
Primary Completion
2017-06-30
Completion
2017-06-30

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03210779 on ClinicalTrials.gov