Atenolol Exposure as Risk for Adverse Metabolic Responses to Beta Blockers
NCT00607347 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 24
Last updated 2011-09-20
Summary
The researchers hypothesize that the impact of increasing systemic exposure to atenolol leads to increased risk for adverse metabolic effects from atenolol therapy in hypertension. This will be accomplished through a 24-hour pharmacokinetic (PK) study and oral glucose tolerance test in hypertensive patients taking chronic atenolol 100 mg daily.
Conditions
Interventions
- OTHER
-
Glucose
Oral Glucose Tolerance Test
Sponsors & Collaborators
-
University of Florida
lead OTHER
Principal Investigators
-
Julie A. Johnson, PharmD · University of Florida
Study Design
- Allocation
- NA
- Purpose
- PREVENTION
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2008-02-29
- Primary Completion
- 2009-06-30
- Completion
- 2009-06-30
Countries
- United States
Study Locations
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