The Effect of Nebivolol on Insulin Sensitivity
NCT00125853 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 54
Last updated 2019-12-12
Summary
The purpose of this study is to conduct a randomised trial to compare the insulin sensitivity, 24 hour blood pressure profile, and tolerability of nebivolol plus a thiazide-like diuretic versus atenolol plus a thiazide-like diuretic.
Conditions
Interventions
- DRUG
-
Nebivolol
Nebivolol 2.5mg daily
- DRUG
-
Atenolol
Atenolol 25mg daily
Sponsors & Collaborators
-
Foundation for Circulatory Health
collaborator OTHER -
Imperial College London
lead OTHER
Principal Investigators
-
Neil R Poulter · Imperial College London
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- SINGLE
- Model
- CROSSOVER
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2006-07-31
- Primary Completion
- 2009-01-31
- Completion
- 2009-01-31
Countries
- United Kingdom
Study Locations
More Related Trials
-
Cardioprotective Effects of Nebivolol Versus Placebo in Patients Undergoing Chemotherapy With Anthracyclines
NCT05728632 ·Status: UNKNOWN ·Phase: PHASE3
-
Efficacy and Safety of Nebivolol Versus Metoprolol in Hypertensive Subject Taking Amlodipine
NCT03635125 ·Status: COMPLETED ·Phase: PHASE4
-
Nebivolol Versus Metoprolol: Sodium Sensitivity
NCT00992056 ·Status: COMPLETED ·Phase: PHASE4
-
Study to Evaluate Effect of Nebivolol on Angina in Women With Microvascular Disease
NCT01665508 ·Status: COMPLETED ·Phase: PHASE4
-
Effects of Nebivolol Versus Metoprolol Succinate on Endothelial Function
NCT01248338 ·Status: COMPLETED ·Phase: PHASE4
-
Dosing Study of the Effects of Nebivolol on Blood Pressure in Black Patients With Mild to Moderate Hypertension
NCT00145236 ·Status: COMPLETED ·Phase: PHASE3
-
A Study Evaluating the Effects of Nebivolol on Blood Pressure in Hypertensive Patients
NCT00200460 ·Status: COMPLETED ·Phase: PHASE3
-
Effects of Nebivolol on Exercise Tolerance and Left Ventricular Systolic and Diastolic Function
NCT01056718 ·Status: COMPLETED ·Phase: NA
-
To Determine the Effect of Nebivolol on Office Blood Pressure of Blacks Residing in Nigeria
NCT03598673 ·Status: COMPLETED
-
Safety Study to Lower the Risk of Heart Failure is Also Effective in Reducing Stiffness of the Arteries
NCT00829296 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Nebivolol in Patients With Systolic Stage 2 Hypertension
NCT01057251 ·Status: COMPLETED ·Phase: PHASE4
-
Effect of Nebivolol on Oxidative Stress and Endothelial Progenitor Cells
NCT01041287 ·Status: COMPLETED ·Phase: PHASE4
-
Evaluation of the Long-term Safety and Tolerability of Metoprolol Versus Nebivolol in Patients With Hypertension
NCT00142584 ·Status: COMPLETED ·Phase: PHASE3
-
The Effect of Nebivolol in Hypertensive Patients With Coronary Artery Disease
NCT00673075 ·Status: COMPLETED ·Phase: PHASE4
-
Impact of Nebivolol on Central Aortic Pressure
NCT01051947 ·Status: WITHDRAWN ·Phase: NA
-
Effect of Nebivolol on the Blood Flow in Hearts of Adults With High Blood Pressure and Abnormal Filling of Heart
NCT01961323 ·Status: COMPLETED ·Phase: PHASE4
-
Comparison of 2 Beta Blocker Drugs on Peripheral Arterial Disease in Patients With High Blood Pressure
NCT01499134 ·Status: COMPLETED ·Phase: PHASE3
-
Study to Assess Efficacy of Nicorandil+Atenolol vs Atenolol in Treatment of Chronic Stable Angina.
NCT01397994 ·Status: UNKNOWN ·Phase: PHASE4
-
Comparative Effect of Nebivolol vs. Metoprolol on Insulin Sensitivity and Fibrinolytic Balance in Metabolic Syndrome
NCT00775671 ·Status: COMPLETED ·Phase: PHASE4
-
Study of the Glycemic Effects of Nebivolol Compared With Metoprolol and HCTZ in Diabetic Hypertensive Patients
NCT00744237 ·Status: COMPLETED ·Phase: PHASE4
-
A Study of the Efficacy and Safety of Nebivolol Added to Existing Antihypertensive Treatment in Patients With Hypertension
NCT00200434 ·Status: COMPLETED ·Phase: PHASE3
-
A Study of the Safety and Efficacy of Long-Term Nebivolol Use in Hypertensive Patients
NCT00200499 ·Status: COMPLETED ·Phase: PHASE3
-
Comparative Effects of Nebivolol and Carvedilol on Diastolic Function in the Elderly Heart Failure Patients
NCT02619526 ·Status: UNKNOWN ·Phase: NA
-
Effects of Nebivolol on Subclinical Left Ventricular dySfunction: A Comparative Study Against Metoprolol
NCT00942487 ·Status: COMPLETED ·Phase: PHASE3
-
Use of Beta-blockers and Risk of New Onset Diabetes
NCT01587638 ·Status: COMPLETED